(Q42870680)

9 November 2017

Key features for designing phosphodiesterase-5 inhibitors (English)

1 reference

9 November 2017

Tung-Ti Chang

1

1 reference

9 November 2017

Hung-Jin Huang

2

1 reference

9 November 2017

Kuei-Jen Lee

3

1 reference

9 November 2017

Hsin Wei Yu

4

1 reference

9 November 2017

Hsin-Yi Chen

5

1 reference

9 November 2017

Fuu-Jen Tsai

6

1 reference

9 November 2017

Mao-Feng Sun

7

1 reference

9 November 2017

Calvin Yu-Chian Chen

8

1 reference

9 November 2017

1 December 2010

1 reference

Journal of Biomolecular Structure and Dynamics

9 November 2017

1 reference

9 November 2017

28

1 reference

9 November 2017

309-321

1 reference

9 November 2017

3

1 reference

3',5'-cyclic nucleotide phosphodiesterase 11A: localization in human tissues

9 November 2017

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Cyclic nucleotide phosphodiesterases: relating structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Erectile dysfunction and its influence on quality of life in patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Antioxidant and antiproliferative activities of Crossostephium chinensis (L.) Makino

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Computer-aided drug design of novel PLA2 inhibitor candidates for treatment of snakebite

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

The effects of deferiprone and deferasirox on the structure and function of beta-thalassemia hemoglobin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Immunoinformatics and modeling perspective of T cell epitope-based cancer immunotherapy: a holistic picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

What is the effective component in suanzaoren decoction for curing insomnia? Discovery by virtual screening and molecular dynamic simulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Ligand-based dual target drug design for H1N1: swine flu--a preliminary first study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

A new method to analyze the similarity of protein structure using TOPS representations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Effects of CMAP and electrostatic cutoffs on the dynamics of an integral membrane protein: the phospholamban study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Molecular modeling and characterization of the B. thuringiensis and B. thuringiensis LDC-9 cytolytic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Molecular dynamics simulations of rhodopsin point mutants at the cytoplasmic side of helices 3 and 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Study of multiple unfolding trajectories and unfolded states of the protein GB1 under the physical property space

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Study of early events in the protein folding of villin headpiece using molecular dynamics simulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Structural and dynamical studies of Humanin in water and TFE/water mixture: a molecular dynamics simulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Investigation of the effect of glycosylation on human prion protein by molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Studies on the structural stability of rabbit prion probed by molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

A docking study using atomistic conformers generated via elastic network model for cyclosporin A/cyclophilin A complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Computational study of the sulfonylated amino acid hydroxamates binding to the zinc ion within the active site of carbonic anhydrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Understanding the structure-activity and structure-selectivity correlation of cyclic guanine derivatives as phosphodiesterase-5 inhibitors by molecular docking, CoMFA and CoMSIA analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

3D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

The Discovery of Tadalafil: A Novel and Highly Selective PDE5 Inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1‘,2‘:1,6]pyrido[3,4-b]indole-1,4-dione Analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

The Discovery of Tadalafil: A Novel and Highly Selective PDE5 Inhibitor. 1: 5,6,11,11a-Tetrahydro-1H-imidazo[1‘,5‘:1,6]pyrido[3,4-b]indole-1,3(2H)-dione Analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Molecular modeling studies of the interaction between Plasmodium falciparum HslU and HslV subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Disruption mechanism in the helix of SPF peptide by interchanging E5 and K10 residues: inference from molecular dynamics study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Molecular modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Conformational dynamics of human AP endonuclease in base excision and nucleotide incision repair pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Sequence analysis, structure prediction, and functional validation of phaC1/phaC2 genes of Pseudomonas sp. LDC-25 and its importance in polyhydroxyalkanoate accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Modification and modificatory kinetics of the active center of prawn beta-N-acetyl-D-glucosaminidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Reconstructing potentials of mean force from short steered molecular dynamics simulations of Vpu from HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

Weighted equation and rules--a novel concept for evaluating protein-ligand interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507361

10.1080/07391102.2010.10507361

21 January 2018

Identifiers

DOI

1 reference

9 November 2017

1 reference