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PCSK9 function and physiology.
scientific article published on July 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
title
PCSK9 function and physiology
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
main subject
physiology
0 references
author
Stephen G. Young
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
Loren G Fong
series ordinal
2
object named as
Loren G Fong
1 reference
stated in
Europe PubMed Central
retrieved
11 January 2020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
PMC publication ID
3837453
author name string
Andrew S Peterson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
publication date
1 July 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
published in
Journal of Lipid Research
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
volume
49
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
page(s)
1595-1599
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
cites work
Plasma PCSK9 preferentially reduces liver LDL receptors in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Functional analysis of sites within PCSK9 responsible for hypercholesterolemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Molecular basis for LDL receptor recognition by PCSK9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
The crystal structure of PCSK9: a regulator of plasma LDL-cholesterol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Effect of mutations in the PCSK9 gene on the cell surface LDL receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Structure of the LDL receptor extracellular domain at endosomal pH
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Deletion of two growth-factor repeats from the low-density-lipoprotein receptor accelerates its degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
27 May 2018
Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
Relation of PCSK9 mutations to serum low-density lipoprotein cholesterol in childhood and adulthood (from The Bogalusa Heart Study).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
Biomedicine. Lowering LDL--not only how low, but how long?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3837453
retrieved
16 August 2018
Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18663786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1194/JLR.CX00001-JLR200
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
PMC publication ID
3837453
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
PubMed publication ID
18663786
1 reference
stated in
Europe PubMed Central
PMC publication ID
3837453
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18663786%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 January 2020
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