(Q42931192)

English

Evolution of human immunodeficiency virus type 1 protease genotypes and phenotypes in vivo under selective pressure of the protease inhibitor ritonavir

scientific article published on August 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Evolution of human immunodeficiency virus type 1 protease genotypes and phenotypes in vivo under selective pressure of the protease inhibitor ritonavir (English)

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

1 reference

based on heuristic

inferred from title

Ronald Swanstrom

5

object named as

Ronald Swanstrom

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

author name string

Wolfgang Resch

1

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Neil Parkin

2

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Terri Watkins

3

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Janera Harris

4

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

language of work or name

0 references

publication date

1 August 2005

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

79

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

16

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

10638-10649

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1182672/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection

1 reference

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Relationship between in vitro human immunodeficiency virus type 1 replication rate and virus load in plasma

1 reference

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A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo

1 reference

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Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control

1 reference

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Selection of high-level resistance to human immunodeficiency virus type 1 protease inhibitors

1 reference

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Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults

1 reference

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Nelfinavir-resistant, amprenavir-hypersusceptible strains of human immunodeficiency virus type 1 carrying an N88S mutation in protease have reduced infectivity, reduced replication capacity, and reduced fitness and process the Gag polyprotein precur

1 reference

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Origin of human immunodeficiency virus type 1 quasispecies emerging after antiretroviral treatment interruption in patients with therapeutic failure

1 reference

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Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease

1 reference

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Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors

1 reference

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Changes in human immunodeficiency virus type 1 populations after treatment interruption in patients failing antiretroviral therapy.

1 reference

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1 reference

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Individual contributions of mutant protease and reverse transcriptase to viral infectivity, replication, and protein maturation of antiretroviral drug-resistant human immunodeficiency virus type 1.

1 reference

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1 reference

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HIV drug resistance and viral fitness.

1 reference

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27 May 2018

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1 reference

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Production of resistant HIV mutants during antiretroviral therapy

1 reference

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Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selection

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27 May 2018

A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

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Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis

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The changing pattern of admissions to a London hospital of patients with HIV: 1988-1997. Royal Free Centre for HIV Medicine.

1 reference

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27 May 2018

Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1.

1 reference

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27 May 2018

Effects of human immunodeficiency virus type 1 resistance to protease inhibitors on reverse transcriptase processing, activity, and drug sensitivity.

1 reference

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Outcome and predictors of failure of highly active antiretroviral therapy: one-year follow-up of a cohort of human immunodeficiency virus type 1-infected persons

1 reference

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Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database

1 reference

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Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.

1 reference

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Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients

1 reference

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Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy

1 reference

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Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo.

1 reference

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

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27 May 2018

Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites

1 reference

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Decay characteristics of HIV-1-infected compartments during combination therapy

1 reference

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27 May 2018

Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors

1 reference

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27 May 2018

Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

1 reference

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Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

1 reference

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Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays.

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Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors

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In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: mutations, kinetics, and frequencies

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Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors

1 reference

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Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1.

1 reference

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In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

1 reference

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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Viral dynamics in human immunodeficiency virus type 1 infection

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Complete nucleotide sequences of functional clones of the AIDS virus

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Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.

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Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.

1 reference

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16 August 2018

Altered viral fitness of HIV-1 following failure of protease inhibitor-based therapy

1 reference

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Fitness of human immunodeficiency virus type 1 protease inhibitor-selected single mutants

1 reference

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Virological and immunological characteristics of HIV treatment failure.

1 reference

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Factors associated with clinical and virological failure in patients receiving a triple therapy including a protease inhibitor.

1 reference

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16 August 2018

Analysis of ritonavir in plasma/serum and tissues by high-performance liquid chromatography.

1 reference

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Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group

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Pre-existence and emergence of drug resistance in HIV-1 infection.

1 reference

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16 August 2018

Predictors of a viral response and subsequent virological treatment failure in patients with HIV starting a protease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in Spain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV type 1 protease cleavage site mutations and viral fitness: implications for drug susceptibility phenotyping assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16051856

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.79.16.10638-10649.2005

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 November 2017

ResearchGate publication ID

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