(Q42940640)

11 November 2017

Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease (English)

1 reference

RAB26, member RAS oncogene family

11 November 2017

0 references

1 reference

regulation of protein catabolic process at presynapse, modulating synaptic transmission

GOA release 2020-03-11

1 reference

Pleckstrin homology domain containing, family G (with RhoGef domain) member 5

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Michael Sendtner

22

1 reference

11 November 2017

Patrick Lüningschrör

1

0 references

Arie Horowitz

Arie Horowitz

11

0 references

Robert Blum

Robert Blum

16

0 references

Reinhard Jahn

Reinhard Jahn

20

0 references

Nurcan Üçeyler

17

Nurcan Üçeyler

1 reference

11 November 2017

18

Susanne Petri

1 reference

11 November 2017

Beyenech Binotti

2

1 reference

11 November 2017

Benjamin Dombert

3

1 reference

11 November 2017

Peter Heimann

4

1 reference

11 November 2017

Angel Perez-Lara

5

1 reference

11 November 2017

Carsten Slotta

6

1 reference

11 November 2017

Nadine Thau-Habermann

7

1 reference

11 November 2017

Cora R von Collenberg

8

1 reference

11 November 2017

Franziska Karl

9

1 reference

11 November 2017

Markus Damme

10

1 reference

11 November 2017

Isabelle Maystadt

12

1 reference

11 November 2017

Annette Füchtbauer

13

1 reference

11 November 2017

Ernst-Martin Füchtbauer

14

1 reference

11 November 2017

Sibylle Jablonka

15

1 reference

11 November 2017

Barbara Kaltschmidt

19

1 reference

11 November 2017

Christian Kaltschmidt

21

1 reference

11 November 2017

language of work or name

English

0 references

publication date

30 October 2017

1 reference

11 November 2017

Nature Communications

1 reference

11 November 2017

8

1 reference

11 November 2017

1

1 reference

11 November 2017

678

1 reference

Creative Commons Attribution 4.0 International

11 November 2017

start time

30 October 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Compartment-Specific Regulation of Autophagy in Primary Neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Electrophysiological Motor Unit Number Estimation (MUNE) Measuring Compound Muscle Action Potential (CMAP) in Mouse Hindlimb Muscles.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Expanding the ubiquitin code through post-translational modification

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Autophagy in synaptic development, function, and pathology

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Compromised autophagy and neurodegenerative diseases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Endplate denervation correlates with Nogo-A muscle expression in amyotrophic lateral sclerosis patients.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The GTPase Rab26 links synaptic vesicles to the autophagy pathway

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

PI(5)P regulates autophagosome biogenesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Membrane dynamics in autophagosome biogenesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

ER Dysfunction and Protein Folding Stress in ALS.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

A current perspective of autophagosome biogenesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Mutations in the PLEKHG5 gene is relevant with autosomal recessive intermediate Charcot-Marie-Tooth disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

PLEKHG5 deficiency leads to an intermediate form of autosomal-recessive Charcot-Marie-Tooth disease

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The unfolded protein response in familial amyotrophic lateral sclerosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Heat shock protein 90 in neurodegenerative diseases

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Mutations of optineurin in amyotrophic lateral sclerosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Methods in mammalian autophagy research

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Nibbling away at synaptic development

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Impaired lysosomal trimming of N-linked oligosaccharides leads to hyperglycosylation of native lysosomal proteins in mice with alpha-mannosidosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Loss of autophagy in the central nervous system causes neurodegeneration in mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Genomewide production of multipurpose alleles for the functional analysis of the mouse genome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Tech: a RhoA GEF selectively expressed in hippocampal and cortical neurons

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

27 May 2018

Synaptic vesicle pools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The gene for a new brain specific RhoA exchange factor maps to the highly unstable chromosomal region 1p36.2-1p36.3.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The guanine nucleotide-binding switch in three dimensions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Quantitative assessment of tactile allodynia in the rat paw

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

An improved perfusion fixation method for the testis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

The distinct genetic pattern of ALS in Turkey and novel mutations.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Regulation of presynaptic neurotransmission by macroautophagy

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

14-3-3ζ binds class III phosphatidylinositol-3-kinase and inhibits autophagy.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Disruption of the CNTF gene results in motor neuron degeneration.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5662736

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-00689-Z

7 January 2021

inferred from DOI database lookup

Respiratory impairment in a mouse model of amyotrophic lateral sclerosis

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-00689-Z

7 January 2021

inferred from DOI database lookup

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-00689-Z

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/S41467-017-00689-Z

1 reference

release_rycbkrjglzd6nh5ion32z4zte4

11 November 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rycbkrjglzd6nh5ion32z4zte4

24 November 2022

mapped directly with Wikidata item

1 reference

11 November 2017

PubMed publication ID

29084947

1 reference