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What causes the death of dopaminergic neurons in Parkinson's disease?
scientific article published on January 2010
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
What causes the death of dopaminergic neurons in Parkinson's disease?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
main subject
Parkinson's disease
1 reference
based on heuristic
inferred from title
dopamine
1 reference
based on heuristic
inferred from title
author
Joshua A Goldberg
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
D James Surmeier
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Jaime N Guzman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Javier Sanchez-Padilla
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
publication date
1 January 2010
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Progress in Brain Research
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
183
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
59-77
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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Chronic systemic pesticide exposure reproduces features of Parkinson's disease
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'Rejuvenation' protects neurons in mouse models of Parkinson's disease
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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
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Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism
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Isradipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cardiovascular disease
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Hypocretin (orexin) loss in Parkinson's disease.
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7 January 2021
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Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein
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Mendelian forms of Parkinson's disease
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Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells
1 reference
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Disease-specific patterns of locus coeruleus cell loss
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The control of firing pattern in nigral dopamine neurons: single spike firing
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Biomedicine. Parkinson's--divergent causes, convergent mechanisms.
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7 January 2021
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N-Methyl-d-Aspartate Antagonists in the Treatment of Parkinson's Disease
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based on heuristic
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Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
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Robust pacemaking in substantia nigra dopaminergic neurons
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7 January 2021
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Calcium signaling and apoptosis
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Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators
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The Free Radical Theory of Aging
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7 January 2021
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Inflammation and dopaminergic neuronal loss in Parkinson's disease: a complex matter.
1 reference
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7 January 2021
based on heuristic
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Parkinson's disease: a dual-hit hypothesis
1 reference
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Crossref
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Neuroinflammation in Parkinson's disease: a target for neuroprotection?
1 reference
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7 January 2021
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Gender-related changes in increase of dopaminergic neurons in the olfactory bulb of Parkinson's disease patients
1 reference
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Clinical trials for neuroprotection in Parkinson's disease: overcoming angst and futility?
1 reference
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7 January 2021
based on heuristic
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Neuroinflammatory processes in Parkinson's disease.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calbindin-D28k in the basal ganglia of patients with parkinsonism
1 reference
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7 January 2021
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A critical reappraisal of current staging of Lewy-related pathology in human brain
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A critical evaluation of current staging of alpha-synuclein pathology in Lewy body disorders
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders
1 reference
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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Pesticide exposure and self-reported Parkinson's disease in the agricultural health study.
1 reference
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration
1 reference
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
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7 January 2021
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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
1 reference
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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
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7 January 2021
based on heuristic
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alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level.
1 reference
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7 January 2021
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Parkinson's disease
1 reference
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
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Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system
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7 January 2021
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Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease.
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(-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.
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[Calcium antagonists of the dihydropyridine type: pharmaceutical chemistry and molecular pharmacology]
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based on heuristic
inferred from DOI database lookup
Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum.
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
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Preservation of hypothalamic dopaminergic neurons in Parkinson's disease.
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aging of the nigrostriatal system in the squirrel monkey
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones
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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-voltage activated calcium currents increase in basal forebrain neurons from aged rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium buffering systems and calcium signaling in aged rat basal forebrain neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress and energy crises in neuronal dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is Parkinson's disease a prion disorder?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell death: the calcium-apoptosis link
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A potential reservoir of immature dopaminergic replacement neurons in the adult mammalian olfactory bulb.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential early markers of Parkinson disease in idiopathic REM sleep behavior disorder.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MPTP as a mitochondrial neurotoxic model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cav1.3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age related mitochondrial degenerative disorders in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Time course of nigrostriatal degeneration in parkinson's disease. A detailed study of influential factors in human brain amine analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular Ca(2+) pools in neuronal signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microdomains of intracellular Ca2+: molecular determinants and functional consequences.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine neurons of the monkey midbrain: contingencies of responses to active touch during self-initiated arm movements.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Medullary catecholaminergic neurons in the normal human brain and in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic role of coenzyme Q(10) in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple Dopamine Functions at Different Time Courses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of glutamate in neurodegeneration of dopamine neurons in several animal models of parkinsonism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histological changes of the dopaminergic nigrostriatal system in aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of voltage-gated L-type Ca2+ channel isoforms for brain function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ionic mechanisms involved in the spontaneous firing of tegmental pedunculopontine nucleus neurons of the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Occupation and risk of parkinsonism: a multicenter case-control study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypocretin (orexin) cell loss in Parkinson's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperpolarization-activated currents, IH and IKIR, in rat dorsal motor nucleus of the vagus neurons in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide flashes in single mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane properties of rat locus coeruleus neurones
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupled oscillator model of the dopaminergic neuron of the substantia nigra
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypothalamic orexin neurons regulate arousal according to energy balance in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2983004-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0079-6123(10)83004-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
20696315
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20696315
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20696315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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