(Q42971222)

English

Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes

scientific article published on June 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

author name string

J Craig Hartman

1

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Kenneth Brouwer

2

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Arun Mandagere

3

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Lawrence Melvin

4

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Richard Gorczynski

5

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

publication date

1 June 2010

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Canadian Journal of Physiology and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

88

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

682-691

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Sitaxsentan therapy for pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Endothelin receptor antagonists in pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Ambrisentan therapy for pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Methods to evaluate biliary excretion of drugs in humans: an updated review

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

In vitro-in vivo correlation of hepatobiliary drug clearance in humans.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Results of European post-marketing surveillance of bosentan in pulmonary hypertension.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Survival with first-line bosentan in patients with primary pulmonary hypertension.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Pregnancy and chronic progressive pulmonary disease

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Inhibition of Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake Is the Major Determinant in the Pharmacokinetic Interaction between Bosentan and Cyclosporin A in the Rat

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Ambrisentan, a non-peptide endothelin receptor antagonist

1 reference

https://api.crossref.org/works/10.1139%2FY10-060

21 January 2018

Identifiers

10.1139/Y10-060

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

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