(Q44655928)

English

Inhibition of Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake Is the Major Determinant in the Pharmacokinetic Interaction between Bosentan and Cyclosporin A in the Rat

scientific article published on November 14, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Inhibition of Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake Is the Major Determinant in the Pharmacokinetic Interaction between Bosentan and Cyclosporin A in the Rat (English)

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

1 reference

based on heuristic

inferred from title

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

molecular medicine

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

pharmacokinetics

1 reference

based on heuristic

inferred from title

Roger Schneiter

2

object named as

Ralph Schneiter

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617681

2 April 2024

author name string

Alexander Treiber

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Stephane Delahaye

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Martine Clozel

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

0 references

publication date

14 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/jpet.103.061614

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Journal of Pharmacology and Experimental Therapeutics

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

308

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

1121-1129

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport

1

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin).

2

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

4

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins

5

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Contribution of mrp2 in alterations of canalicular bile formation by the endothelin antagonist bosentan

6

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver

8

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Drug Metabolism and Disposition

9

27

173

publication date

1999

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Simultaneous determination of bosentan and its three major metabolites in various biological matrices and species using narrow bore liquid chromatography with ion spray tandem mass spectrometric detection

10

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Clinical Pharmacokinetics of Atorvastatin

11

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Drug Metabolism and Disposition

12

18

158

publication date

1990

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Life-threatening interaction of mibefradil and beta-blockers with dihydropyridine calcium channel blockers

13

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.

14

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Bosentan therapy for pulmonary arterial hypertension

16

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

18

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport

19

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein

20

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Pathology and Biology

21

47

182

publication date

1999

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Pharmacokinetic interaction between oral cyclosporin and mibefradil in stabilized post-renal-transplant patients

22

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

23

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole

24

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

25

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Drug Metabolism and Disposition

26

27

810

publication date

1999

1 reference

10.1124/JPET.103.061614

https://api.crossref.org/works/10.1124/JPET.103.061614

2 April 2024

Identifiers

10.1124/JPET.103.061614

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

release_4xq5irxfpnbe7nlntcc2rgkzmy

1 reference

https://api.fatcat.wiki/v0/release/4xq5irxfpnbe7nlntcc2rgkzmy

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

ResearchGate publication ID

0 references

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