(Q42976899)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610758%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice (English)

1 reference

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7 February 2020

0 references

0 references

6

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7 February 2020

7

Irene Knuesel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610758%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Samira Kocherhans

1

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7 February 2020

Amrita Madhusudan

2

1 reference

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7 February 2020

Jana Doehner

3

1 reference

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7 February 2020

Karin S Breu

4

1 reference

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7 February 2020

Roger M Nitsch

5

1 reference

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7 February 2020

language of work or name

English

0 references

publication date

1 July 2010

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7 February 2020

published in

Journal of Neuroscience

1 reference

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7 February 2020

volume

30

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7 February 2020

page(s)

9228-9240

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7 February 2020

issue

27

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describes a project that uses

7 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632461/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Reelin, the extracellular matrix protein deficient in reeler mutant mice, is processed by a metalloproteinase.

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

1 reference

12 December 2020

Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody

1 reference

12 December 2020

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

12 December 2020

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

1 reference

12 December 2020

Increased vulnerability to kainate-induced seizures in utrophin-knockout mice

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Secreted Reelin molecules form homodimers.

1 reference

12 December 2020

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning

1 reference

12 December 2020

Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta

1 reference

12 December 2020

A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signaling

1 reference

12 December 2020

Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade

1 reference

12 December 2020

Genetic modulation of tau phosphorylation in the mouse.

1 reference

12 December 2020

Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer's disease.

1 reference

12 December 2020

Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission.

1 reference

12 December 2020

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

1 reference

12 December 2020

Tumor necrosis factor-alpha, interleukin-1beta, and interferon-gamma stimulate gamma-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway

1 reference

12 December 2020

Deciphering the molecular basis of memory failure in Alzheimer's disease

1 reference

12 December 2020

Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin

1 reference

12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

12 December 2020

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2

1 reference

12 December 2020

Reelin modulates NMDA receptor activity in cortical neurons.

1 reference

12 December 2020

Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity

1 reference

12 December 2020

Reelin expression and glycosylation patterns are altered in Alzheimer's disease

1 reference

12 December 2020

Neuropsychology in Alzheimer's disease and other dementia research

1 reference

12 December 2020

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

12 December 2020

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

1 reference

12 December 2020

Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

1 reference

12 December 2020

DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing

1 reference

12 December 2020

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

1 reference

12 December 2020

Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus.

1 reference

12 December 2020

Pathways by which Abeta facilitates tau pathology

1 reference

12 December 2020

ApoE receptor 2 controls neuronal survival in the adult brain.

1 reference

12 December 2020

Reelin signaling facilitates maturation of CA1 glutamatergic synapses

1 reference

12 December 2020

Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice

1 reference

12 December 2020

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

1 reference

12 December 2020

The killing of neurons by beta-amyloid peptides, prions, and pro-inflammatory cytokines

1 reference

12 December 2020

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

12 December 2020

Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons.

1 reference

12 December 2020

Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors

1 reference

12 December 2020

1 reference

12 December 2020

Regulated proteolysis of APP and ApoE receptors

1 reference

12 December 2020

Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting

1 reference

12 December 2020

The RELN locus in Alzheimer's disease

1 reference

12 December 2020

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

1 reference

12 December 2020

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

1 reference

12 December 2020

Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications

1 reference

12 December 2020

Apolipoprotein E receptors in the nervous system

1 reference

12 December 2020

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth

1 reference

12 December 2020

Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging

1 reference

12 December 2020

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease

1 reference

12 December 2020

Co-localization of Reelin and proteolytic AbetaPP fragments in hippocampal plaques in aged wild-type mice

1 reference

12 December 2020

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

12 December 2020

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

1 reference

12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

12 December 2020

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

12 December 2020

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

12 December 2020

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

12 December 2020

1 reference

12 December 2020

Evolution of the neuropathology of Alzheimer's disease.

1 reference

12 December 2020

Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain

1 reference

12 December 2020

10.1523/JNEUROSCI.0418-10.2010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610758%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

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7 February 2020

1 reference