(Q42985589)

12 November 2017

title

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment (English)

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Indian Genome Variation Consortium

12 November 2017

author

16

object named as

Indian Genome Variation Consortium

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12 November 2017

17

Ritushree Kukreti

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12 November 2017

Sandeep Grover

1

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12 November 2017

Mandaville Gourie-Devi

2

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12 November 2017

Ruchi Baghel

3

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12 November 2017

Sangeeta Sharma

4

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12 November 2017

Kiran Bala

5

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12 November 2017

Meena Gupta

6

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12 November 2017

Krishnamoorthy Narayanasamy

7

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12 November 2017

Binuja Varma

8

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12 November 2017

Meenal Gupta

9

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12 November 2017

Kavita Kaur

10

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12 November 2017

Puneet Talwar

11

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12 November 2017

Harpreet Kaur

12

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12 November 2017

Sudheer Giddaluru

13

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12 November 2017

Abhay Sharma

14

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12 November 2017

Samir K Brahmachari

15

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12 November 2017

publication date

1 July 2010

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12 November 2017

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12 November 2017

volume

11

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12 November 2017

issue

7

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12 November 2017

page(s)

927-941

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Prevalence of neurological disorders in Bangalore, India: a community-based study with a comparison between urban and rural areas

12 November 2017

cites work

1 reference

Challenges in the management of epilepsy in resource-poor countries

21 January 2018

1 reference

The Indian Genome Variation database (IGVdb): a project overview

21 January 2018

1 reference

Genetic landscape of the people of India: a canvas for disease gene exploration

21 January 2018

1 reference

Allele and genotype frequency of CYP2C19 in a Tamilian population

21 January 2018

1 reference

No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population

21 January 2018

1 reference

A simple salting out procedure for extracting DNA from human nucleated cells

21 January 2018

1 reference

Association mapping in structured populations

21 January 2018

1 reference

Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites

21 January 2018

1 reference

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

21 January 2018

1 reference

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

1 reference

Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.

21 January 2018

1 reference

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

21 January 2018

1 reference

Update on pharmacogenetics in epilepsy: a brief review.

21 January 2018

1 reference

The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement

21 January 2018

1 reference

Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.

21 January 2018

1 reference

The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics

21 January 2018

1 reference

Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients

21 January 2018

1 reference

CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects

21 January 2018

1 reference

CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population

21 January 2018

1 reference

Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients.

21 January 2018

1 reference

Effect of CYP2C19 genetic polymorphism on pharmacokinetics of phenytoin and phenobarbital in Japanese epileptic patients using Non-linear Mixed Effects Model approach.

21 January 2018

1 reference

Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy

21 January 2018

1 reference

A major influence of CYP2C19 genotype on the steady-state concentration of N-desmethylclobazam

21 January 2018

1 reference

Impact of CYP2C19 polymorphisms on the efficacy of clobazam therapy

21 January 2018

1 reference

Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems

21 January 2018

1 reference

Increased transcriptional activity of the CYP3A4*1B promoter variant

21 January 2018

1 reference

CYP3A4 gene polymorphisms influence testosterone 6beta-hydroxylation

21 January 2018

1 reference

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

21 January 2018

1 reference

Non-synonymous single nucleotide alterations in the microsomal epoxide hydrolase gene and their functional effects

21 January 2018

1 reference

Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.

21 January 2018

1 reference

Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes

21 January 2018

1 reference

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

21 January 2018

1 reference

N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.

21 January 2018

1 reference

Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10

21 January 2018

1 reference

Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes.

21 January 2018

1 reference

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine

21 January 2018

1 reference

Several major antiepileptic drugs are substrates for human P-glycoprotein

21 January 2018

1 reference

Interaction of antiepileptic drugs with human P-glycoprotein in vitro

21 January 2018

1 reference

P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

21 January 2018

1 reference

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

21 January 2018

1 reference

Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese

21 January 2018

1 reference

Multidrug-resistant genotype (ABCB1) and seizure recurrence in newly treated epilepsy: data from international pharmacogenetic cohorts

21 January 2018

1 reference

Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey

21 January 2018

1 reference

Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese

21 January 2018

1 reference

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

21 January 2018

1 reference

Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients.

21 January 2018

1 reference

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients

21 January 2018

1 reference

Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study

21 January 2018

1 reference

Phenytoin and carbamazepine: potential- and frequency-dependent block of Na currents in mammalian myelinated nerve fibers

21 January 2018

1 reference

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

21 January 2018

1 reference

Association between SCN1A polymorphism and carbamazepine-resistant epilepsy

21 January 2018

1 reference

A functional polymorphism in the SCN1A gene is not associated with carbamazepine dosages in Austrian patients with epilepsy

21 January 2018

1 reference

A splice site variant in the sodium channel gene SCN1A confers risk of febrile seizures

21 January 2018

1 reference

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

21 January 2018

1 reference

21 January 2018

1 reference

An epilepsy mutation in the beta1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin

21 January 2018

1 reference

SCN1A, SCN1B, and GABRG2 gene mutation analysis in Chinese families with generalized epilepsy with febrile seizures plus.

21 January 2018

1 reference

Lack of an association between candidate gene loci and idiopathic generalized epilepsy in Kuwaiti Arab children

21 January 2018

1 reference

A missense mutation of the Na+ channel alpha II subunit gene Na(v)1.2 in a patient with febrile and afebrile seizures causes channel dysfunction

21 January 2018

1 reference

A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose

21 January 2018

1 reference

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population

21 January 2018

1 reference

SCN2A Mutations and Benign Familial Neonatal-Infantile Seizures: The Phenotypic Spectrum

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/PGS.10.62

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12 November 2017

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