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Update on pharmacogenetics in epilepsy: a brief review.
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1 reference
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Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Update on pharmacogenetics in epilepsy: a brief review
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author
Cassandra Szoeke
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Samuel Berkovic
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author name string
Mark Newton
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2
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Julie M Wood
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
David Goldstein
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Terrence J OBrien
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
Les J Sheffield
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
publication date
1 February 2006
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
published in
Lancet Neurology
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
volume
5
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
page(s)
189-196
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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7 January 2021
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7 January 2021
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Quality of life of people with epilepsy: a European study
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7 January 2021
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The genetics of human epilepsy
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Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs
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Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene
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Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: comparison of inbred strains.
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Repeated neural tube defects and valproate monotherapy suggest a pharmacogenetic abnormality
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Genetic predisposition to phenytoin-induced birth defects
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7 January 2021
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Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin
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7 January 2021
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A novel SCN1A mutation associated with generalized epilepsy with febrile seizures plus--and prevalence of variants in patients with epilepsy
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TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients.
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Medical genetics: a marker for Stevens-Johnson syndrome
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Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.
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Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy
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Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy.
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MDR1 gene expression in brain of patients with medically intractable epilepsy
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Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
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7 January 2021
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Interaction of antiepileptic drugs with human P-glycoprotein in vitro
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7 January 2021
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Carbamazepine is not a substrate for P-glycoprotein
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Crossref
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7 January 2021
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Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy
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Crossref
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7 January 2021
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7 January 2021
based on heuristic
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The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes
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7 January 2021
based on heuristic
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Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele
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7 January 2021
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Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene
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7 January 2021
based on heuristic
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Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein
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7 January 2021
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The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
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7 January 2021
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Metabolism and excretion of mood stabilizers and new anticonvulsants
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7 January 2021
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inferred from DOI database lookup
Carnitine transport: pathophysiology and metabolism of known molecular defects
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites
1 reference
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reference URL
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7 January 2021
based on heuristic
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Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
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Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study
1 reference
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7 January 2021
based on heuristic
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Multidrug resistance proteins in tuberous sclerosis and refractory epilepsy.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel mechanism underlying drug resistance in chronic epilepsy
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
GABA(B) receptor 1 polymorphism (G1465A) is associated with temporal lobe epilepsy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant
1 reference
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
MDR1 single nucleotide polymorphisms: multiplicity of haplotypes and functional consequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the human major vault protein in gangliogliomas.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochromes P450 and metabolism of xenobiotics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal sodium-channel alpha1-subunit mutations in generalized epilepsy with febrile seizures plus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An association between mesial temporal lobe epilepsy with hippocampal sclerosis and human leukocyte antigens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of age and polytherapy, risk factors of valproic acid (VPA) hepatotoxicity, on the excretion of thiol conjugates of (E)-2,4-diene VPA in people with epilepsy taking VPA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Science, medicine, and the future: Pharmacogenetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multidrug resistance transporters and modulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantifying the costs of serious adverse drug reactions to antiepileptic drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estimating the cost of epilepsy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical significance of the cytochrome P450 2C19 genetic polymorphism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacogenomics and the evolution of healthcare : is it time for cost-effectiveness analysis at the individual level?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970352-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1474-4422(06)70352-0
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PubMed ID
16426995
1 reference
stated in
Europe PubMed Central
PubMed ID
16426995
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16426995%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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