(Q43041655)

12 November 2017

title

A novel high throughput screening assay for HCV NS3 serine protease inhibitors (English)

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12 November 2017

9

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12 November 2017

7

Avi Golan-Goldhirsh

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12 November 2017

Yevgeny Berdichevsky

1

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12 November 2017

Romy Zemel

2

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12 November 2017

Larisa Bachmatov

3

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12 November 2017

Alex Abramovich

4

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12 November 2017

Ruth Koren

5

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12 November 2017

Peramachi Sathiyamoorthy

6

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12 November 2017

Ran Tur-Kaspa

8

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12 November 2017

publication date

1 February 2003

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Journal of Virological Methods

12 November 2017

published in

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12 November 2017

volume

107

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12 November 2017

issue

2

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12 November 2017

page(s)

245-255

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Candidate targets for hepatitis C virus-specific antiviral therapy

12 November 2017

cites work

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Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

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Matrix-Assisted Refolding of Single-Chain Fv– Cellulose Binding Domain Fusion Proteins

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Identification and characterization of a histone binding site of the non-structural protein 3 of hepatitis C virus

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Characterisation of non-structural protein 3 of hepatitis C virus as modulator of protein phosphorylation mediated by PKA and PKC: evidences for action on the level of substrate and enzyme

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7 January 2021

An in vitro assay for hepatitis C virus NS3 serine proteinase.

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Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinomas in Europe: results of a European concerted action

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7 January 2021

A high-throughput radiometric assay for hepatitis C virus NS3 protease

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In vitro cleavage of hepatitis C virus polyprotein substrates by purified recombinant NS3 protease

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7 January 2021

Engineering, characterization and phage display of hepatitis C virus NS3 protease and NS4A cofactor peptide as a single-chain protein

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Establishment of an in vitro assay to characterize hepatitis C virus NS3-4A protease trans-processing activity

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7 January 2021

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7 January 2021

Complex formation of the nonstructural protein 3 of hepatitis C virus with the p53 tumor suppressor

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7 January 2021

Non-peptide inhibitors of HCV serine proteinase

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7 January 2021

A high throughput assay of the hepatitis C virus nonstructural protein 3 serine proteinase

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7 January 2021

C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity

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7 January 2021

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

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7 January 2021

Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing

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7 January 2021

Hepatitis C virus NS3/4A protease

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7 January 2021

p53-dependent transcriptional repression of p21(waf1) by hepatitis C virus NS3.

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7 January 2021

The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay

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7 January 2021

Use of a fluorescence plate reader for measuring kinetic parameters with inner filter effect correction

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7 January 2021

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

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7 January 2021

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

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7 January 2021

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7 January 2021

Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon-alpha

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

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7 January 2021

Establishment of an in vitro assay system for screening hepatitis C virus protease inhibitors using high performance liquid chromatography

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7 January 2021

An enzyme-linked immunosorbent assay for detecting proteolytic activity of hepatitis C virus proteinase

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7 January 2021

A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates

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7 January 2021

Construction, expression, and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease

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7 January 2021

Cell transformation induced by hepatitis C virus NS3 serine protease

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7 January 2021

A continuous spectrophotometric assay for the hepatitis C virus serine protease

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7 January 2021

10.1016/S0166-0934(02)00255-0

Identifiers

DOI

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12 November 2017

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