(Q43094359)

English

Glycolysis inhibition decreases the levels of glutamate transporters and enhances glutamate neurotoxicity in the R6/2 Huntington's disease mice

scientific article published on 18 April 2010

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scholarly article

1 reference

Europe PubMed Central

13 November 2017

Glycolysis inhibition decreases the levels of glutamate transporters and enhances glutamate neurotoxicity in the R6/2 Huntington's disease mice (English)

1 reference

Europe PubMed Central

13 November 2017

Huntington's disease

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1 reference

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inferred from title

toxic encephalopathy

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author name string

Ana María Estrada-Sánchez

1

1 reference

Europe PubMed Central

13 November 2017

Teresa Montiel

2

1 reference

Europe PubMed Central

13 November 2017

Lourdes Massieu

3

1 reference

Europe PubMed Central

13 November 2017

publication date

18 April 2010

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Europe PubMed Central

13 November 2017

Neurochemical Research

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Europe PubMed Central

13 November 2017

35

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Europe PubMed Central

13 November 2017

8

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Europe PubMed Central

13 November 2017

1156-1163

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Europe PubMed Central

13 November 2017

https://scigraph.springernature.com/pub.10.1007/s11064-010-0168-5

0 references

Glucose can fuel glutamate uptake in ischemic brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0168-5

21 January 2018

Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0168-5

21 January 2018

1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers

1 reference

https://api.crossref.org/works/10.1007%2FS11064-010-0168-5

21 January 2018

Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glutamate uptake in the R6 Huntington's disease transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-dependent production of reactive oxygen species is involved in neuronal damage induced during glycolysis inhibition in cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate efflux via the reversal of the sodium-dependent glutamate transporter caused by glycolytic inhibition in rat cultured astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolically derived aspartate--elevated extracellular levels in vivo in lodoacetate poisoning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iodoacetate produces striatal excitotoxic lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease--an in situ hybridization study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A possible mechanism for the hypoxia-hypoglycemia-induced release of excitatory amino acids from cultured hippocampal astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological classification of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain glyceraldehyde-3-phosphate dehydrogenase activity in human trinucleotide repeat disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-inhibition of glutamate transport prevents excitatory amino acid-induced glycolysis in astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective defect of in vivo glycolysis in early Huntington's disease striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An energy budget for signaling in the grey matter of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local injection of antisense oligonucleotides targeted to the glial glutamate transporter GLAST decreases the metabolic response to somatosensory activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of nordihydroguaiaretic acid on iodoacetate-induced toxicity in cultured neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate uptake is reduced in prefrontal cortex in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained metabolic inhibition induces an increase in the content and phosphorylation of the NR2B subunit of N-methyl-D-aspartate receptors and a decrease in glutamate transport in the rat hippocampus in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20401690

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-010-0168-5

1 reference

Europe PubMed Central

13 November 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

13 November 2017

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