(Q43116111)

14 November 2017

title

Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice (English)

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14 November 2017

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hepatic gluconeogenesis

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12

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14 November 2017

Y Fujita

1

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14 November 2017

M Hosokawa

2

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14 November 2017

S Fujimoto

3

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14 November 2017

E Mukai

4

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14 November 2017

A Abudukadier

5

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14 November 2017

A Obara

6

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14 November 2017

M Ogura

7

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14 November 2017

Y Nakamura

8

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14 November 2017

K Toyoda

9

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14 November 2017

K Nagashima

10

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14 November 2017

Y Seino

11

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14 November 2017

publication date

29 March 2010

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14 November 2017

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14 November 2017

volume

53

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14 November 2017

issue

7

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14 November 2017

page(s)

1472-1481

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Role of AMP-activated protein kinase in mechanism of metformin action

14 November 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00125-010-1729-5

Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets

21 January 2018

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12 December 2020

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

1 reference

12 December 2020

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

1 reference

12 December 2020

Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

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12 December 2020

Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

1 reference

12 December 2020

Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species

1 reference

12 December 2020

Curcumin inhibits glucose production in isolated mice hepatocytes

1 reference

12 December 2020

Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.

1 reference

12 December 2020

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

1 reference

12 December 2020

AMP-activated protein kinase--development of the energy sensor concept.

1 reference

12 December 2020

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12 December 2020

2,7-Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation

1 reference

12 December 2020

Nitric oxide and peroxynitrite in health and disease

1 reference

12 December 2020

AMP-activated protein kinase phosphorylation of endothelial NO synthase

1 reference

12 December 2020

Management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy. Update regarding the thiazolidinediones.

1 reference

12 December 2020

Prior exposure to high glucose augments depolarization-induced insulin release by mitigating the decline of ATP level in rat islets

1 reference

12 December 2020

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 reference

12 December 2020

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

12 December 2020

Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes.

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12 December 2020

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

1 reference

12 December 2020

Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.

1 reference

12 December 2020

Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets

1 reference

12 December 2020

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

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12 December 2020

Oxidation of 2',7'-dichlorofluorescin by peroxynitrite

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12 December 2020

Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus.

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12 December 2020

Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

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12 December 2020

The AMP-activated protein kinase pathway--new players upstream and downstream.

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12 December 2020

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

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12 December 2020

Metformin therapy and clinical uses

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12 December 2020

Local Nitric Oxide Synthase Inhibition Reduces Skeletal Muscle Glucose Uptake but Not Capillary Blood Flow During In Situ Muscle Contraction in Rats

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12 December 2020

Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species

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12 December 2020

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

1 reference

12 December 2020

Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes.

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12 December 2020

Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase

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12 December 2020

Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration

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12 December 2020

10.1007/S00125-010-1729-5

Identifiers

DOI

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14 November 2017

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