(Q43121322)

14 November 2017

title

4SC-101, a novel immunosuppressive drug, inhibits IL-17 and attenuates colitis in two murine models of inflammatory bowel disease (English)

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inflammatory bowel diseases

14 November 2017

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9

Aldo Ammendola

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14 November 2017

Leo R Fitzpatrick

1

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14 November 2017

Ludwig Deml

2

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14 November 2017

Claudia Hofmann

3

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14 November 2017

Jeffrey S Small

4

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14 November 2017

Manfred Groeppel

5

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14 November 2017

Svetlana Hamm

6

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14 November 2017

Sylvia Lemstra

7

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14 November 2017

Johann Leban

8

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14 November 2017

language of work or name

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1 October 2010

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Inflammatory Bowel Diseases

14 November 2017

published in

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14 November 2017

volume

16

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14 November 2017

issue

10

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14 November 2017

page(s)

1763-1777

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From immunogenic mechanisms to novel therapeutic approaches in inflammatory bowel disease

14 November 2017

cites work

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Novel treatment options for inflammatory bowel disease: targeting alpha 4 integrin.

21 January 2018

1 reference

Leflunomide treatment of Crohn's disease patients intolerant to standard immunomodulator therapy

21 January 2018

1 reference

Treatment of Crohn's disease with leflunomide as second-line immunosuppression : a phase 1 open-label trial on efficacy, tolerability and safety

21 January 2018

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The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase

21 January 2018

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Mechanism of action for leflunomide in rheumatoid arthritis

21 January 2018

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Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide.

21 January 2018

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Leflunomide in the treatment of rheumatoid arthritis.

21 January 2018

1 reference

SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors

21 January 2018

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Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis

21 January 2018

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Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

21 January 2018

1 reference

In vitro and in vivo effects of the probiotic Escherichia coli strain M-17: immunomodulation and attenuation of murine colitis

21 January 2018

1 reference

Interleukin-23/Th17 pathways and inflammatory bowel disease

21 January 2018

1 reference

Increased expression of interleukin 17 in inflammatory bowel disease

21 January 2018

1 reference

The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice.

21 January 2018

1 reference

Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile

21 January 2018

1 reference

Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells

21 January 2018

1 reference

Functional relevance of soluble TNF-alpha, transmembrane TNF-alpha and TNF-signal transduction in gastrointestinal diseases with special reference to inflammatory bowel diseases

21 January 2018

1 reference

IL-23/IL-17 immunity as a hallmark of Crohn's disease

21 January 2018

1 reference

Differential effect of thalidomide and dexamethasone on the transcription factor NF-kappa B.

21 January 2018

1 reference

TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.

21 January 2018

1 reference

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

Critical appraisal of the current practice in murine TNBS-induced colitis

21 January 2018

1 reference

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IBD.21264

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14 November 2017

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