(Q43129380)

14 November 2017

title

Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase Cgamma2. (English)

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14 November 2017

M Elvers

1

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14 November 2017

R Pozgaj

2

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14 November 2017

I Pleines

3

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14 November 2017

F May

4

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14 November 2017

M J E Kuijpers

5

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14 November 2017

J M W Heemskerk

6

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14 November 2017

P Yu

7

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14 November 2017

B Nieswandt

8

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14 November 2017

publication date

3 March 2010

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Journal of Thrombosis and Haemostasis

14 November 2017

published in

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14 November 2017

volume

8

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14 November 2017

issue

6

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14 November 2017

page(s)

1353-1363

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Platelets in atherothrombosis

14 November 2017

cites work

1 reference

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21 January 2018

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Adhesion mechanisms in platelet function

21 January 2018

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In vivo thrombus formation in murine models

21 January 2018

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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

21 January 2018

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Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation.

21 January 2018

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Activation of platelet function through G protein-coupled receptors

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Cell adhesion mechanisms in platelets

21 January 2018

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A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

21 January 2018

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Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry

21 January 2018

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Characterization of phospholipase C gamma enzymes with gain-of-function mutations

21 January 2018

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Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha

21 January 2018

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Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

21 January 2018

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Rat platelets are deficient in internal Ca2+ release and require influx of extracellular Ca2+ for activation

21 January 2018

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Rac1 is essential for phospholipase C-gamma2 activation in platelets

21 January 2018

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Involvement of Src kinases and PLCgamma2 in clot retraction

21 January 2018

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Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow.

21 January 2018

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Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

21 January 2018

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Dual role of collagen in factor XII-dependent thrombus formation

21 January 2018

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MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice

21 January 2018

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A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1

21 January 2018

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Murine GPVI stimulates weak integrin activation in PLCgamma2-/- platelets: involvement of PLCgamma1 and PI3-kinase

21 January 2018

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Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity

21 January 2018

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Platelet collagen receptors and coagulation. A characteristic platelet response as possible target for antithrombotic treatment

21 January 2018

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Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2010.03838.X

Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other?

21 January 2018

1 reference

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Differential involvement of Galpha16 in CC chemokine-induced stimulation of phospholipase Cbeta, ERK, and chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2010.03838.X

Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice

21 January 2018

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Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2010.03838.X

10.1111/J.1538-7836.2010.03838.X

21 January 2018

Identifiers

DOI

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14 November 2017

1 reference