(Q43154680)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Snake phospholipase A2 neurotoxins enter neurons, bind specifically to mitochondria, and open their transition pores (English)

1 reference

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14 January 2020

1 reference

5

1 reference

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14 January 2020

Paolo Bernardi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Marco Paoli

2

1 reference

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14 January 2020

7

Cesare Montecucco

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Michela Rigoni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Eva Milanesi

3

1 reference

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14 January 2020

Paola Caccin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

language of work or name

English

0 references

publication date

22 September 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

14 January 2020

published in

1 reference

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14 January 2020

volume

283

1 reference

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14 January 2020

issue

49

1 reference

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14 January 2020

page(s)

34013-34020

1 reference

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describes a project that uses

14 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2662223/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Presynaptic neurotoxins with enzymatic activities

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A2.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Mitochondrial Ca2+ as a key regulator of cell life and death

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Presynaptic enzymatic neurotoxins.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

The mitochondrial permeability transition from in vitro artifact to disease target

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

How proteins produce cellular membrane curvature

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Taipoxin induces synaptic vesicle exocytosis and disrupts the interaction of synaptophysin I with VAMP2.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Ammodytoxin, a neurotoxic secreted phospholipase A(2), can act in the cytosol of the nerve cell

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Protein-Lipid Interplay in Fusion and Fission of Biological Membranes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Nerve terminal damage by beta-bungarotoxin: its clinical significance

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Neuromuscular effects of Papuan Taipan snake venom

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Novel reticular calcium binding protein is purified on taipoxin columns.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Mitochondria and sarcoplasmic reticulum as model targets for neurotoxic and myotoxic phospholipases A2.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Beta-bungarotoxin inhibition of calcium accumulation by rat brain mitochondria.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Chemical modification of taipoxin and the consequences for phospholipase activity, pathophysiology, and inhibition of high-affinity choline uptake

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Envenoming bites by kraits: the biological basis of treatment-resistant neuromuscular paralysis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Beta-bungarotoxin-induced depletion of synaptic vesicles at the mammalian neuromuscular junction

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

R25 is an intracellular membrane receptor for a snake venom secretory phospholipase A(2).

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3 protein gamma and epsilon isoforms

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Beta-bungarotoxin is a potent inducer of apoptosis in cultured rat neurons by receptor-mediated internalization

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

A high affinity acceptor for phospholipase A2 with neurotoxic activity is a calmodulin.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662223

The eloquent ape: genes, brains and the evolution of language

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M803243200

The effects of taipoxin and notexin on the function and fine structure of the murine neuromuscular junction

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M803243200

A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M803243200

The role of phospholipase activity in the action of a presynaptic neurotoxin from the venom of Notechis scutatus scutatus (australian tiger snake)

21 January 2018

1 reference

12 December 2020

Mode of neuromuscular blocking action of toxic phospholipases A2 from Vipera ammodytes venom

1 reference

12 December 2020

Morphological changes induced by crotoxin in murine nerve and neuromuscular junction

1 reference

12 December 2020

Histidine 21 is at the NAD+ binding site of diphtheria toxin

1 reference

12 December 2020

Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins

1 reference

12 December 2020

Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique

1 reference

12 December 2020

Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products

1 reference

12 December 2020

Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells

1 reference

12 December 2020

Ultrastructural changes in the motor nerve terminals caused by β-bungarotoxin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M803243200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18809685%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference