(Q43183133)

15 November 2017

title

Toward a consensus model of the HERG potassium channel (English)

1 reference

15 November 2017

Ulrich Zachariae

4

0 references

Johan Åqvist

6

object named as

Johan Aqvist

1 reference

15 November 2017

Anna Stary

1

1 reference

15 November 2017

Sören J Wacker

2

1 reference

15 November 2017

Lars Boukharta

3

1 reference

15 November 2017

Yasmin Karimi-Nejad

5

1 reference

15 November 2017

Gert Vriend

7

1 reference

15 November 2017

Bert L de Groot

8

1 reference

15 November 2017

publication date

1 March 2010

1 reference

15 November 2017

1 reference

15 November 2017

volume

5

1 reference

15 November 2017

issue

3

1 reference

15 November 2017

page(s)

455-467

1 reference

The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.

15 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

I(Kr): the hERG channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

HERG K+ channels: friend and foe.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Understanding the Structure−Activity Relationship of the Human Ether-a-go-go-Related Gene Cardiac K+ Channel. A Model for Bad Behavior

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Medicinal chemistry of hERG optimizations: Highlights and hang-ups

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A structural basis for drug-induced long QT syndrome

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Modeling the hERG potassium channel in a phospholipid bilayer: Molecular dynamics and drug docking studies

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Drug block of the hERG potassium channel: insight from modeling.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A two-state homology model of the hERG K+ channel: application to ligand binding

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Exploring blocker binding to a homology model of the open hERG K+ channel using docking and molecular dynamics methods

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

The relation between the divergence of sequence and structure in proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Database of homology-derived protein structures and the structural meaning of sequence alignment

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Crystal structure and mechanism of a calcium-gated potassium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

X-ray structure of a voltage-dependent K+ channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular determinants of hERG channel block by terfenadine and cisapride

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A conserved glutamate is important for slow inactivation in K+ channels.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Structural and functional role of the extracellular s5-p linker in the HERG potassium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Characterization of a novel missense mutation E637K in the pore-S6 loop of HERG in a patient with long QT syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Local quality assessment in homology models using statistical potentials and support vector machines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Models of the structure and gating mechanisms of the pore domain of the NaChBac ion channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A common architecture for K+ channels and ionotropic glutamate receptors?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular ordering of interfacially localized tryptophan analogs in ester- and ether-lipid bilayers studied by 2H-NMR.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Statistical analysis of predicted transmembrane alpha-helices.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Role of aromatic localization in the gating process of a potassium channel.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A measure of helical propensity for amino acids in membrane environments

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Membrane protein structure quality in molecular dynamics simulation.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Membrane simulations: bigger and better?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular dynamics simulations and membrane protein structure quality.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Structural model of the Ca V 1.2 pore

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Interactions of H562 in the S5 helix with T618 and S621 in the pore helix are important determinants of hERG1 potassium channel structure and function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Topological mapping of the asymmetric drug binding to the human ether-à-go-go-related gene product (HERG) potassium channel by use of tandem dimers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Physicochemical features of the HERG channel drug binding site

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular determinants of dofetilide block of HERG K+ channels.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Mechanism of action of a novel human ether-a-go-go-related gene channel activator

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Comparative protein structure modeling of genes and genomes

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Errors in protein structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Using multiple templates to improve quality of homology models in automated homology modeling.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Fold helical proteins by energy minimization in dihedral space and a DFIRE-based statistical energy function.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

The ModFOLD server for the quality assessment of protein structural models

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Improving sequence-based fold recognition by using 3D model quality assessment

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Benchmarking consensus model quality assessment for protein fold recognition.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Protein secondary structure prediction based on position-specific scoring matrices

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

GROMACS 3.0: a package for molecular simulation and trajectory analysis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Setting up and optimization of membrane protein simulations.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Ion permeation mechanism of the potassium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Comparison of simple potential functions for simulating liquid water

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Very fast empirical prediction and rationalization of protein pKa values

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900461

7 January 2021

Identifiers

DOI

10.1002/CMDC.200900461

1 reference

15 November 2017

1 reference