(Q43186370)

English

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes.

scientific article published on 22 January 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094062%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094062%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Thomas Reinheckel

3

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17 January 2020

6

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17 January 2020

author name string

C Oberle

1

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17 January 2020

J Huai

2

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17 January 2020

M Tacke

4

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17 January 2020

M Rassner

5

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17 January 2020

J Buellesbach

7

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17 January 2020

C Borner

8

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17 January 2020

publication date

22 January 2010

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17 January 2020

Cell Death & Differentiation

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17 January 2020

17

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17 January 2020

7

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17 January 2020

1167-1178

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17 January 2020

https://scigraph.springernature.com/pub.10.1038/cdd.2009.214

0 references

Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole

1 reference

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21 January 2018

H2O2-mediated damage to lysosomal membranes of J-774 cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent

1 reference

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21 January 2018

Induction of cell death by the lysosomotropic detergent MSDH.

1 reference

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21 January 2018

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Sphingosine-induced apoptosis is dependent on lysosomal proteases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Lysosomal membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Apoptotic pathways: involvement of lysosomal proteases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Lysosomes in cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Mitochondrial membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Lysosomal membrane permeabilization during apoptosis--involvement of Bax?

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Bax inhibition protects against free fatty acid-induced lysosomal permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Lysosomal destabilization in p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Delayed oxidant-induced cell death involves activation of phospholipase A2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cathepsin B mediates tumor necrosis factor-induced arachidonic acid release in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Global mapping of the topography and magnitude of proteolytic events in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Sensitization to the lysosomal cell death pathway upon immortalization and transformation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cell death by necrosis: towards a molecular definition

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

21 January 2018

Differential release of alkaline deoxyribonuclease and of glutamate dehydrogenase from rat-liver mitochondrial fractions

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

7 January 2021

based on heuristic

inferred from DOI database lookup

Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

7 January 2021

based on heuristic

inferred from DOI database lookup

The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.214

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CDD.2009.214

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094062%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20094062%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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