(Q40096579)

17 September 2017

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins (English)

1 reference

17 September 2017

1 reference

5

Gregory J Gores

1 reference

17 September 2017

Nathan W Werneburg

1

1 reference

17 September 2017

M Eugenia Guicciardi

series ordinal

2

1 reference

17 September 2017

Steve F Bronk

series ordinal

3

1 reference

17 September 2017

Scott H Kaufmann

series ordinal

4

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17 September 2017

language of work or name

English

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publication date

8 August 2007

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Journal of Biological Chemistry

17 September 2017

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17 September 2017

282

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17 September 2017

39

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17 September 2017

28960-28970

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Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

17 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Safety and antitumor activity of recombinant soluble Apo2 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Apoptosis-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

TRAIL and apoptosis induction by TNF-family death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Apo2L/TRAIL and its death and decoy receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Interleukin-6 contributes to Mcl-1 up-regulation and TRAIL resistance via an Akt-signaling pathway in cholangiocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Life in the balance: how BH3-only proteins induce apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

21 January 2018

Lysosomes in cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Synergistic movements of Ca(2+) and Bax in cells undergoing apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

NAPO as a novel marker for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

From receptors to stress-activated MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Further study on the role of HSP70 on Ca2+ homeostasis in rat ventricular myocytes subjected to simulated ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Tumor necrosis factor: an apoptosis JuNKie?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Lysosomal membrane permeabilization during apoptosis--involvement of Bax?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

Sensitization to the lysosomal cell death pathway upon immortalization and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705671200

21 January 2018

Identifiers

DOI

10.1074/JBC.M705671200

1 reference

17 September 2017

1 reference