(Q43194318)

English

Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway

scientific article published in December 2008

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scholarly article

1 reference

Europe PubMed Central

15 November 2017

Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway (English)

1 reference

Europe PubMed Central

15 November 2017

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craniosynostosis

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6

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Europe PubMed Central

15 November 2017

object named as

Richard Jäger

2

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author name string

Anne Moenning

1

1 reference

Europe PubMed Central

15 November 2017

Angela Egert

3

1 reference

Europe PubMed Central

15 November 2017

Wolfram Kress

4

1 reference

Europe PubMed Central

15 November 2017

Eva Wardelmann

5

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Europe PubMed Central

15 November 2017

language of work or name

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publication date

1 December 2008

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Europe PubMed Central

15 November 2017

Molecular and Cellular Biology

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Europe PubMed Central

15 November 2017

29

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Europe PubMed Central

15 November 2017

3

1 reference

Europe PubMed Central

15 November 2017

881-891

1 reference

Europe PubMed Central

15 November 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2630675/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development

1 reference

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Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer.

1 reference

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25 May 2018

Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene

1 reference

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25 May 2018

Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation

1 reference

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25 May 2018

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

1 reference

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25 May 2018

Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors

1 reference

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A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential

1 reference

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25 May 2018

MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element

1 reference

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25 May 2018

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

1 reference

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25 May 2018

Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells

1 reference

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The BMP antagonist noggin regulates cranial suture fusion

1 reference

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25 May 2018

PDGFRA activating mutations in gastrointestinal stromal tumors.

1 reference

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25 May 2018

Transcription factor gene AP-2 gamma essential for early murine development

1 reference

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25 May 2018

A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation

1 reference

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25 May 2018

Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5

1 reference

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25 May 2018

A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene

1 reference

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A role of PDGFRalpha in basal cell carcinoma proliferation

1 reference

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Genetics of craniofacial development and malformation

1 reference

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25 May 2018

Developmental roles of platelet-derived growth factors

1 reference

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25 May 2018

New developments in cranial suture research

1 reference

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Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis

1 reference

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25 May 2018

Cbfa1 isoforms exert functional differences in osteoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

25 May 2018

Generalized lacZ expression with the ROSA26 Cre reporter strain

1 reference

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25 May 2018

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

25 May 2018

Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

25 May 2018

Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3' -kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

25 May 2018

The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites

1 reference

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Spina bifida occulta in homozygous Patch mouse embryos.

1 reference

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25 May 2018

Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation

1 reference

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25 May 2018

Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

1 reference

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Studies in cranial suture biology: in vitro cranial suture fusion

1 reference

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25 May 2018

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

1 reference

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Molecular biology of matrix vesicles.

1 reference

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25 May 2018

Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors

1 reference

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Craniosynostosis update 1987.

1 reference

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25 May 2018

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation

1 reference

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Human osteoblasts synthesize and respond to platelet-derived growth factor

1 reference

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Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5

1 reference

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Inorganic phosphate added exogenously or released from beta-glycerophosphate initiates mineralization of osteoid nodules in vitro

1 reference

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Determination and expression of platelet-derived growth factor-AA in bone cell cultures

1 reference

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25 May 2018

Developmental expression of the alpha receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation

1 reference

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Enhanced purification of cell-permeant Cre and germline transmission after transduction into mouse embryonic stem cells.

1 reference

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Erk pathways negatively regulate matrix mineralization

1 reference

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1 reference

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1 reference

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Differential growth factor control of bone formation through osteoprogenitor differentiation

1 reference

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Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation.

1 reference

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15 August 2018

Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

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Tissue origins and interactions in the mammalian skull vault

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

15 August 2018

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630675

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Platelet-derived growth factor (PDGF) receptor-alpha activates c-Jun NH2-terminal kinase-1 and antagonizes PDGF receptor-beta -induced phenotypic transformation

1 reference

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Integration of FGF and TWIST in calvarial bone and suture development.

1 reference

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1 reference

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A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1 reference

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Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis

1 reference

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Craniosynostoses: phenotypic/molecular correlations

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Distribution of platelet-derived growth factor (PDGF) A chain mRNA, protein, and PDGF-alpha receptor in rapidly forming human bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

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Induction of vascular endothelial growth factor by IGF-I in osteoblast-like cells is mediated by the PI3K signaling pathway through the hypoxia-inducible factor-2alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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inferred from PubMed ID database lookup

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

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based on heuristic

inferred from PubMed ID database lookup

Regulation and role of PDGF receptor alpha-subunit expression during embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of systemically administered PDGF-BB on the rodent skeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion of the frontal suture in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The combination of platelet-derived growth factor-BB and insulin-like growth factor-I stimulates bone repair in adult Yucatan miniature pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19047372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00885-08

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

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