(Q43219125)

16 November 2017

title

Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). (English)

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Carmen Schade-Brittinger

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object named as

Carmen Schade-Brittinger

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Günther Deuschl

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Thomas Klockgether

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Claudia Trenkwalder

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Friederike Sixel-Döring

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object named as

Friederike Sixel-Döring

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Thomas Gasser

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Werner Poewe

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Gregor Wenning

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Klaus Seppi

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Wolfgang H Oertel

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Karla Eggert

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Richard Dodel

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Annika Spottke

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Nicole Schimke

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Christoph Kamm

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Martin Sawires

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Felix Geser

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Martin Köllensperger

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Christine Daniels

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Alexander Gerhard

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Alexander Reuss

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Sylvia Reinecker

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Birgit Herting

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Manja Kloss

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Martin Krause

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Silke Böttger

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Markus Naumann

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Axel Lipp

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Doreen Gruber

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Andreas Kupsch

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Yansheng Du

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16 November 2017

language of work or name

English

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publication date

1 January 2010

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volume

25

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issue

1

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page(s)

97-107

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16 November 2017

cites work

Multiple system atrophy

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Microglial activation parallels system degeneration in multiple system atrophy

21 January 2018

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Microglial activation in multiple system atrophy: a potential role for NF-kappaB/rel proteins.

21 January 2018

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Cell death mechanisms in multiple system atrophy.

21 January 2018

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Microglia: phagocyte and glia cell.

21 January 2018

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Degeneration of neuronal cells due to oxidative stress--microglial contribution

21 January 2018

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[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.

21 January 2018

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Treatment of early seropositive rheumatoid arthritis: a two-year, double-blind comparison of minocycline and hydroxychloroquine

21 January 2018

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Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

21 January 2018

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Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

21 January 2018

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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

21 January 2018

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Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

21 January 2018

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Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.

21 January 2018

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Minocycline treatment attenuates microglia activation and non-angiotensin II [125I] CGP42112 binding in brainstem following nodose ganglionectomy.

21 January 2018

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Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus

21 January 2018

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Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

21 January 2018

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Minocycline attenuates T cell and microglia activity to impair cytokine production in T cell-microglia interaction

21 January 2018

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Rise and fall of minocycline in neuroprotection: need to promote publication of negative results

21 January 2018

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Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease

21 January 2018

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Neuroprotection in Huntington's disease: a 2-year study on minocycline

21 January 2018

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Maintained improvement with minocycline of a patient with advanced Huntington's disease

21 January 2018

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Minocycline in amyotrophic lateral sclerosis: a pilot study

21 January 2018

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Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

21 January 2018

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Minocycline treatment in acute stroke: an open-label, evaluator-blinded study.

21 January 2018

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The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study

21 January 2018

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Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS).

21 January 2018

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EQ-5D: a measure of health status from the EuroQol Group

21 January 2018

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In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

21 January 2018

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Parametric imaging of ligand-receptor binding in PET using a simplified reference region model.

21 January 2018

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Simplified reference tissue model for PET receptor studies.

21 January 2018

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Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures.

21 January 2018

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A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

21 January 2018

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A pilot clinical trial of creatine and minocycline in early Parkinson disease: 18-month results

21 January 2018

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Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

21 January 2018

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In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy

21 January 2018

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Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MDS.22732

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16 November 2017

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