(Q43233333)

English

Overexpression of the NHE1 isoform of the Na(+)/H (+) exchanger causes elevated apoptosis in isolated cardiomyocytes after hypoxia/reoxygenation challenge

scientific article published in December 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

Overexpression of the NHE1 isoform of the Na(+)/H (+) exchanger causes elevated apoptosis in isolated cardiomyocytes after hypoxia/reoxygenation challenge (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

1 reference

based on heuristic

inferred from title

2

object named as

Larry Fliegel

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

author name string

Pratap Karki

1

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

publication date

1 December 2009

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

338

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

47-57

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0337-5

21 January 2018

Molecular biology of the myocardial Na+/H+ exchanger

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0337-5

21 January 2018

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na+/H+ exchanger isoform 1 facilitates cardiomyocyte embryonic stem cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological profile of KR-33028, a highly selective inhibitor of Na+/H+ exchanger.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Na+/H+ exchanger isoform 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of the ischaemic myocardium by Na+/H+ exchange inhibitors: potential mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial reperfusion injury: etiology, mechanisms, and therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting Na+/H+ exchanger regulation for cardiac protection: a RSKy approach?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene inactivation of Na+/H+ exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-sensing receptors induce apoptosis in cultured neonatal rat ventricular cardiomyocytes during simulated ischemia/reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sarcolemmal Na+/H+ exchanger activity and expression in human ventricular myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Na+/H+ exchange isoform 1 mRNA expression in isolated rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the protein and cDNA of the cardiac Na+/H+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in human acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinase-dependent activation of the Na+/H+ exchanger is mediated through phosphorylation of amino acids Ser770 and Ser771.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(+)/H(+) exchange inhibitors for cardioprotective therapy: progress, problems and prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic NHE-1 blockade induces an antiapoptotic effect in the hypertrophied heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of expression of the sodium-hydrogen exchanger in rat myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis as a therapeutic target in acutely ischemic myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of polar amino-acid residues in membrane associated regions of the NHE1 isoform of the mammalian Na+/H+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct initiator caspases are required for the induction of apoptosis in cardiac myocytes during ischaemia versus reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase-mediated regulation of the Na(+)/H(+) exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of extracellular signal-regulated kinase during silibinin-protected, isoproterenol-induced apoptosis in rat cardiac myocytes is tyrosine kinase pathway-mediated and protein kinase C-dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orally administered NHE1 inhibitor cariporide reduces acute responses to coronary occlusion and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiomyocyte death induced by myocardial ischemia and reperfusion: measurement with recombinant human annexin-V in a mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenylephrine and sustained acidosis activate the neonatal rat cardiomyocyte Na+/H+ exchanger through phosphorylation of amino acids Ser770 and Ser771.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Na+/H+ exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional analysis of the Na+/H+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early apoptosis in human myocardial infarcts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological role and regulation of the Na+/H+ exchanger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cariporide attenuates myocardial ischaemia, reperfusion injury and apoptosis in isolated rat hearts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and characterization of the Na+/H+ exchanger in the mammalian myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Na(+)/H(+) exchanger: a target for cardiac therapeutic intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/19949839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-009-0337-5

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 November 2017

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