(Q43240756)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

1 reference

1

1 reference

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17 February 2020

author name string

John R Ussher

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Jagdip S Jaswal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Monique Raubenheimer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Victoria H M Lam

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Cory S Wagg

6

1 reference

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17 February 2020

Gary D Lopaschuk

7

1 reference

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17 February 2020

language of work or name

English

0 references

publication date

8 November 2012

1 reference

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17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

3

1 reference

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17 February 2020

page(s)

711-720

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

17 February 2020

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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25 May 2018

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25 May 2018

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Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

25 May 2018

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Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.

25 May 2018

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Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

25 May 2018

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High-fat diets cause insulin resistance despite an increase in muscle mitochondria

25 May 2018

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25 May 2018

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Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

25 May 2018

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Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse

25 May 2018

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Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

25 May 2018

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

25 May 2018

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Regulation of sarcolemmal transport of substrates in the healthy and diseased heart.

25 May 2018

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Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs.

25 May 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

25 May 2018

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The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

25 May 2018

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25 May 2018

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A simple method for the isolation and purification of total lipides from animal tissues

15 August 2018

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Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Two mechanisms produce tissue-specific inhibition of fatty acid oxidation by oxfenicine

25 May 2018

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25 May 2018

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Inhibition by etomoxir of carnitine palmitoyltransferase I reduces hepatic glucose production and plasma lipids in non-insulin-dependent diabetes mellitus.

25 May 2018

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25 May 2018

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15 August 2018

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Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse

15 August 2018

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15 August 2018

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15 August 2018

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Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Etomoxir, a fatty acid oxidation inhibitor, increases food intake and reduces hepatic energy status in rats

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581198

Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet

29 September 2018

1 reference

12 December 2020

Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research

1 reference

12 December 2020

Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance

1 reference

12 December 2020

Mechanism of action of oxfenicine on muscle metabolism

1 reference

12 December 2020

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

12 December 2020

Cardiac Hypertrophy in the Dog and Rat Induced by Oxfenicine, an Agent Which Modifies Muscle Metabolism

1 reference

12 December 2020

A sensitive radioisotopic assay of pyruvate dehydrogenase complex in human muscle tissue

1 reference

12 December 2020

Etomoxir, sodium 2-[6-(4-chlorophenoxy)hexyl] oxirane-2-carboxylate, inhibits triacylglycerol depletion in hepatocytes and lipolysis in adipocytes

1 reference

12 December 2020

Effects of the carnitine-acyltransferase inhibitor etomoxir on insulin sensitivity, energy expenditure and substrate oxidation in NIDDM

1 reference

12 December 2020

Hypoglycemic effects of a novel fatty acid oxidation inhibitor in rats and monkeys

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB12-0259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

23139350

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23139350%20AND%20SRC:MED&resulttype=core&format=json