(Q43292835)

English

Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease.

scientific article published in August 2009

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scholarly article

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Europe PubMed Central

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5 February 2020

Age-dependent impairment of spine morphology and synaptic plasticity in hippocampal CA1 neurons of a presenilin 1 transgenic mouse model of Alzheimer's disease (English)

1 reference

Europe PubMed Central

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5 February 2020

Alzheimer's disease

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synaptic plasticity

1 reference

based on heuristic

inferred from title

6

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5 February 2020

Mariaelena Repici

3

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5 February 2020

Catherine Rovira

7

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5 February 2020

author name string

Alexandra Auffret

1

1 reference

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5 February 2020

Vanessa Gautheron

2

1 reference

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5 February 2020

Rudolf Kraftsik

4

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5 February 2020

Howard T J Mount

5

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5 February 2020

language of work or name

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publication date

1 August 2009

1 reference

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5 February 2020

Journal of Neuroscience

1 reference

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5 February 2020

29

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5 February 2020

32

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5 February 2020

10144-10152

1 reference

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5 February 2020

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spine changes associated with hippocampal long-term synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic bias in an "unbiased" neuronal counting technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that overexpress the human APP695SWE mutant form of amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological changes in dendritic spines associated with long-term synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of dendritic spines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease is a synaptic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APP processing and synaptic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of long-term potentiation in aged rats involves perforated synapses but dendritic spine branching results from high-frequency stimulation alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the role of presenilins beyond Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spines and long-term plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological and physiological functions of presenilins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomical and physiological plasticity of dendritic spines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protracted synaptogenesis after activity-dependent spinogenesis in hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid modulation of synaptic transmission and plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spine expansion and stabilization associated with long-term potentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Making the best of brain slices: comparing preparative methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for vibratome sectioning of Golgi-Cox stained whole rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19675248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1856-09.2009

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19675248%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19675248%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19675248%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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