(Q43420262)

English

Theoretical analysis of interplay of therapeutic protein drug and circulating soluble target: temporal profiles of 'free' and 'total' drug and target

scientific article published on 26 May 2011

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scholarly article

1 reference

Europe PubMed Central

23 November 2017

Theoretical analysis of interplay of therapeutic protein drug and circulating soluble target: temporal profiles of 'free' and 'total' drug and target (English)

1 reference

Europe PubMed Central

23 November 2017

author name string

Cuyue Tang

1

1 reference

Europe PubMed Central

23 November 2017

Thomayant Prueksaritanont

2

1 reference

Europe PubMed Central

23 November 2017

publication date

26 May 2011

1 reference

Europe PubMed Central

23 November 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

23 November 2017

28

1 reference

Europe PubMed Central

23 November 2017

10

1 reference

Europe PubMed Central

23 November 2017

2447-2457

1 reference

Europe PubMed Central

23 November 2017

Antibody pharmacokinetics and pharmacodynamics

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Pharmacokinetic and pharmacodynamic modeling of humanized anti-factor IX antibody (SB 249417) in humans.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Numerical validation and properties of a rapid binding approximation of a target-mediated drug disposition pharmacokinetic model.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Target-mediated drug disposition model: relationships with indirect response models and application to population PK-PD analysis.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep.

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Integrated cellular bone homeostasis model for denosumab pharmacodynamics in multiple myeloma patients

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VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

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https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0471-0

21 January 2018

A single ascending dose study of bapineuzumab in patients with Alzheimer disease

1 reference

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21 January 2018

Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation.

1 reference

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21 January 2018

Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies

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21 January 2018

Population pharmacokinetics and pharmacodynamics of the anti-CD11a antibody hu1124 in human subjects with psoriasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21614635

12 December 2020

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Nonlinear pharmacokinetics of recombinant human macrophage colony-stimulating factor (M-CSF) in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21614635

12 December 2020

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Bioanalytical approaches to quantify "total" and "free" therapeutic antibodies and their targets: technical challenges and PK/PD applications over the course of drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21614635

12 December 2020

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Pharmacokinetics of anti-hepcidin monoclonal antibody Ab 12B9m and hepcidin in cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/21614635

12 December 2020

based on heuristic

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Pharmacokinetics and pharmacodynamics of a humanized monoclonal antibody to factor IX in cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/21614635

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-011-0471-0

1 reference

Europe PubMed Central

23 November 2017

1 reference

Europe PubMed Central

23 November 2017

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