(Q43491158)

24 November 2017

Hypoxia promotes the production and inhibits the destruction of human articular cartilage (English)

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24 November 2017

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Brendan L Thoms

1

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24 November 2017

Katarzyna A Dudek

series ordinal

2

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24 November 2017

Jérôme E Lafont

series ordinal

3

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24 November 2017

Christopher L Murphy

series ordinal

4

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24 November 2017

1 May 2013

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24 November 2017

Arthritis & Rheumatology

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24 November 2017

65

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24 November 2017

5

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24 November 2017

1302-1312

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Disease-modifying therapies for osteoarthritis : current status

24 November 2017

1 reference

21 January 2018

1 reference

Measurement of pH and ionic composition of pericellular sites

21 January 2018

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The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules

21 January 2018

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Control of human articular chondrocyte differentiation by reduced oxygen tension

21 January 2018

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Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways

21 January 2018

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Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages

21 January 2018

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Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension.

21 January 2018

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Sustained hypoxia enhances chondrocyte matrix synthesis

21 January 2018

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Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes.

21 January 2018

1 reference

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

21 January 2018

1 reference

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

Hypoxia-inducible factors and the response to hypoxic stress

21 January 2018

1 reference

The human side of hypoxia-inducible factor

21 January 2018

1 reference

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

HIF-1 and HIF-2: working alone or together in hypoxia?

21 January 2018

1 reference

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

21 January 2018

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Hypoxia, RONS and energy metabolism in articular cartilage

21 January 2018

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Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage.

21 January 2018

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Interleukin-1 and osteoarthritis

21 January 2018

1 reference

Inhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes

21 January 2018

1 reference

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

21 January 2018

1 reference

Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage

21 January 2018

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The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

21 January 2018

1 reference

Sox9 is required for cartilage formation

21 January 2018

1 reference

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

21 January 2018

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SOX9 directly regulates the type-II collagen gene

21 January 2018

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SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6.

21 January 2018

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TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors

21 January 2018

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

21 January 2018

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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

21 January 2018

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Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

21 January 2018

1 reference

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

21 January 2018

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Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

21 January 2018

1 reference

Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy

21 January 2018

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Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia

21 January 2018

1 reference

Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling

21 January 2018

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Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis

21 January 2018

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A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.37867

1 reference

24 November 2017

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