(Q43545560)

English

Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210.

scientific article published in March 2001

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scholarly article

1 reference

Europe PubMed Central

24 November 2017

Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210. (English)

1 reference

Europe PubMed Central

24 November 2017

0 references

Plasmodium falciparum

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based on heuristic

inferred from title

Saccharomyces cerevisiae

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author name string

Ferlan JT

1

1 reference

Europe PubMed Central

24 November 2017

Mookherjee S

2

1 reference

Europe PubMed Central

24 November 2017

Okezie IN

3

1 reference

Europe PubMed Central

24 November 2017

Fulgence L

4

1 reference

Europe PubMed Central

24 November 2017

Sibley CH

5

1 reference

Europe PubMed Central

24 November 2017

publication date

1 March 2001

1 reference

Europe PubMed Central

24 November 2017

Molecular and Biochemical Parasitology

1 reference

Europe PubMed Central

24 November 2017

113

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Europe PubMed Central

24 November 2017

139-150

1 reference

Europe PubMed Central

24 November 2017

1

1 reference

Europe PubMed Central

24 November 2017

Antimalarial drug resistance: the pace quickens

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Epidemiology of drug resistance in malaria

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Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa

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Drug resistance and the P-glycoprotein homologues of Plasmodium falciparum

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Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites

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Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain.

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Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum

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Direct evidence that asparagine at position 108 of the Plasmodium falciparum dihydrofolate reductase is involved in resistance to antifolate drugs in Tanzania

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Pyrimethamine-resistant Plasmodium falciparum parasites among Tanzanian children: a facility-based study using the polymerase chain reaction.

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Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthetase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania

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High prevalence of mutations in the dihydrofolate reductase gene of Plasmodium falciparum in isolates from Tanzania without evidence of an association to clinical sulfadoxine/pyrimethamine resistance.

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Resistance to pyrimethamine/sulfadoxine in Plasmodium falciparum in 12 villages in north east Tanzania and a test of chlorproguanil/dapsone

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Mutant dihydrofolate reductase-thymidylate synthase genes in pyrimethamine-resistant Plasmodium falciparum with polymorphic chromosome duplications.

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Plasmodium falciparum: induction, selection, and characterization of pyrimethamine-resistant mutants.

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Pyrimethamine resistant mutations in Plasmodium falciparum

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Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

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Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea

1 reference

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Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

1 reference

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Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa.

1 reference

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Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria

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Genetic analysis of Plasmodium falciparum infections on the north-western border of Thailand.

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Molecular assays for surveillance of antifolate-resistant malaria

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The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites

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Analysis of the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene sequence.

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Plasmodium falciparum: detection of antifolate resistance by mutation-specific restriction enzyme digestion.

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Association between antifol resistance in vitro and DHFR gene point mutation in Plasmodium falciparum isolates

1 reference

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Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

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Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.

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Molecular epidemiology of malaria in Yaounde, Cameroon I. Analysis of point mutations in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.

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Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

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Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building.

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Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance

1 reference

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1 reference

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Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum

1 reference

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1 reference

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1 reference

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Nucleotide sequence of the dihydrofolate reductase gene of Saccharomyces cerevisiae

1 reference

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Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

10.1016/S0166-6851(01)00207-9

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

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