(Q43548465)

English

In vivo PDGF beta receptor activation in the dorsocaudal brainstem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD.

scientific article published in March 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 November 2017

In vivo PDGF beta receptor activation in the dorsocaudal brainstem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD. (English)

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Europe PubMed Central

PubMed publication ID

24 November 2017

Nicholas J Szerlip

2

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Szerlip NJ

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Europe PubMed Central

PubMed publication ID

24 November 2017

author name string

Simakajornboon N

1

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Europe PubMed Central

PubMed publication ID

24 November 2017

Gozal E

3

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Europe PubMed Central

PubMed publication ID

24 November 2017

Anonetapipat JW

4

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Europe PubMed Central

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24 November 2017

Gozal D

5

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24 November 2017

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publication date

1 March 2001

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24 November 2017

number of pages

8

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inferred from page(s)

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Europe PubMed Central

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24 November 2017

895

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Europe PubMed Central

PubMed publication ID

24 November 2017

1-2

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Europe PubMed Central

PubMed publication ID

24 November 2017

111-118

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

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Expression of interleukin-1 beta converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery

1 reference

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7 January 2021

bcl-2 prolongs neuronal survival during hypoxia-induced apoptosis

1 reference

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Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

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Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia

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PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways.

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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7 January 2021

Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis

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7 January 2021

Hypoxia induces c-Fos protein expression in NMDA but not AMPA glutamate receptor labeled neurons within the nucleus tractus solitarii of the conscious rat.

1 reference

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7 January 2021

Brainstem activation of platelet-derived growth factor-beta receptor modulates the late phase of the hypoxic ventilatory response

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Protein kinase C modulation of ventilatory response to hypoxia in nucleus tractus solitarii of conscious rats

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7 January 2021

NF-kappaB induction during in vivo hypoxia in dorsocaudal brain stem of rat: effect of MK-801 and L-NAME.

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7 January 2021

Hypoxia induces selective SAPK/JNK-2-AP-1 pathway activation in the nucleus tractus solitarii of the conscious rat.

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7 January 2021

Mechanism of action and in vivo role of platelet-derived growth factor

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7 January 2021

Global ischemia induces apoptosis-associated genes in hippocampus

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7 January 2021

Induction of platelet-derived growth factor beta-receptor in focal ischemia of rat brain.

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Neurotrophin signal transduction in the nervous system

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7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

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7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

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7 January 2021

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

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7 January 2021

Expression of platelet-derived growth factor B-chain and beta-receptor in hypoxic/ischemic encephalopathy of neonatal rats

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7 January 2021

Major differences in response to graded hypoxia between hypoglossal and neocortical neurons

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7 January 2021

The combination of bcl-2 expression and NGF-deprivation facilitates the selective destruction of BAD protein in living sympathetic neurons.

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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7 January 2021

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model

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Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

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7 January 2021

Hypoxia induces activation of a N-methyl-D-aspartate glutamate receptor-protein kinase C pathway in the dorsocaudal brainstem of the conscious rat

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7 January 2021

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF

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The Akt proto-oncogene links Ras to Pak and cell survival signals

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Dependence of autocrine growth factor stimulation in platelet-derived growth factor-B-induced mouse brain tumor cells

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Signal transduction by receptors with tyrosine kinase activity

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Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function.

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Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

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7 January 2021

Identifiers

10.1016/S0006-8993(01)02054-6

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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