(Q43558721)

24 November 2017

title

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy (English)

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24 November 2017

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anti-retroviral agent

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Nadezda Apostolova

1

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author name string

Leysa J Gomez-Sucerquia

2

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24 November 2017

Anna Gortat

3

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24 November 2017

Ana Blas-Garcia

4

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24 November 2017

Juan V Esplugues

5

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24 November 2017

language of work or name

English

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publication date

2 August 2011

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24 November 2017

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24 November 2017

volume

54

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24 November 2017

issue

3

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24 November 2017

page(s)

1009-1019

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Increasing burden of liver disease in patients with HIV infection

24 November 2017

cites work

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Clinical syndromes and consequences of antiretroviral-related hepatotoxicity

21 January 2018

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Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors

21 January 2018

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Central role of mitochondria in metabolic regulation of liver pathophysiology

21 January 2018

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Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus

21 January 2018

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Lipid changes in patients initiating efavirenz- and indinavir-based antiretroviral regimens

21 January 2018

1 reference

Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring

21 January 2018

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An extremely different dysmetabolic profile between the two available nonnucleoside reverse transcriptase inhibitors: efavirenz and nevirapine

21 January 2018

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Efavirenz: a decade of clinical experience in the treatment of HIV.

21 January 2018

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Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor

21 January 2018

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Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.

21 January 2018

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Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells

21 January 2018

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Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells

21 January 2018

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21 January 2018

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Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

21 January 2018

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CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients

21 January 2018

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Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine

21 January 2018

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Influence of liver fibrosis stage on plasma levels of efavirenz in HIV-infected patients with chronic hepatitis B or C.

21 January 2018

1 reference

Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis.

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells

21 January 2018

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Autophagy: assays and artifacts

21 January 2018

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

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Autophagy in metazoans: cell survival in the land of plenty

21 January 2018

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Autophagy fights disease through cellular self-digestion

21 January 2018

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Selective degradation of mitochondria by mitophagy

21 January 2018

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Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

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The role of autophagy in cancer development and response to therapy.

21 January 2018

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Autophagosomes: biogenesis from scratch?

21 January 2018

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Imiquimod simultaneously induces autophagy and apoptosis in human basal cell carcinoma cells

21 January 2018

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21 January 2018

Autophagy in the liver

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Autophagy in liver diseases.

21 January 2018

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Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice.

21 January 2018

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Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress

21 January 2018

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Autophagy inhibition enhances apoptosis induced by ginsenoside Rk1 in hepatocellular carcinoma cells

21 January 2018

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21 January 2018

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Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

21 January 2018

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The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells

21 January 2018

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CH05-10, a novel indinavir analog, is a broad-spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/HEP.24459

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24 November 2017

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