(Q43601697)

25 November 2017

title

Visualization of bisphosphonate-induced caspase-3 activity in apoptotic osteoclasts in vitro (English)

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25 November 2017

0 references

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Benford HL

1

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25 November 2017

McGowan NW

2

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25 November 2017

Helfrich MH

3

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25 November 2017

Nuttall ME

4

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25 November 2017

Rogers MJ

5

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25 November 2017

publication date

1 May 2001

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25 November 2017

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25 November 2017

volume

28

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25 November 2017

issue

5

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25 November 2017

page(s)

465-473

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Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry.

25 November 2017

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7 January 2021

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

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7 January 2021

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

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7 January 2021

Human osteoclast formation and activity in vitro: effects of alendronate.

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7 January 2021

Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro

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7 January 2021

Caspases: the executioners of apoptosis

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7 January 2021

Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

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7 January 2021

The mitochondrial permeability transition pore and its role in cell death

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7 January 2021

A new method to isolate large numbers of rabbit osteoclasts and osteoclast-like cells: application to the characterization of serum response element binding proteins during osteoclast differentiation

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7 January 2021

Glucocorticoids inhibit bone resorption by isolated rat osteoclasts by enhancing apoptosis

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7 January 2021

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7 January 2021

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

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7 January 2021

Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

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7 January 2021

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

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7 January 2021

Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound

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7 January 2021

Etidronate (EHDP) inhibits osteoclastic-bone resorption, promotes apoptosis and disrupts actin rings in isolate-mature osteoclasts.

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7 January 2021

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

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7 January 2021

Ultrastructural and cytochemical studies on cell death of osteoclasts induced by bisphosphonate treatment.

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7 January 2021

Localization of mitochondria in living cells with rhodamine 123

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7 January 2021

Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates

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7 January 2021

Mitochondrial control of cell death

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7 January 2021

Mechanisms mediating caspase activation in cell death

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7 January 2021

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

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7 January 2021

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

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7 January 2021

Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

1 reference

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7 January 2021

Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: evidence from structure-activity relationships in J774 macrophages.

1 reference

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7 January 2021

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

1 reference

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7 January 2021

Osteoclast demise in the rat: physiological versus degenerative cell death

1 reference

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7 January 2021

Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation

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7 January 2021

BM 21.0955, a potent new bisphosphonate to inhibit bone resorption

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7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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7 January 2021

Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2801%2900412-4

7 January 2021

Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes

1 reference

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7 January 2021

Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism

1 reference

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7 January 2021

Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum.

1 reference

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7 January 2021

Metabolism of halogenated bisphosphonates by the cellular slime mould dictyostelium discoideum

1 reference

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7 January 2021

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure

1 reference

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7 January 2021

Quantitative morphometric evaluation of the inhibitory activity of new aminobisphosphonates on bone resorption in the rat.

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7 January 2021

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

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7 January 2021

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

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7 January 2021

Substrate specificities of caspase family proteases

1 reference

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7 January 2021

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2801%2900412-4

7 January 2021

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2801%2900412-4

7 January 2021

Prenyltransferase inhibitors induce apoptosis in proliferating thyroid cells through a p53-independent CrmA-sensitive, and caspase-3-like protease-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS8756-3282%2801%2900412-4

7 January 2021

10.1016/S8756-3282(01)00412-4

Identifiers

DOI

1 reference

25 November 2017

1 reference