(Q43636939)

English

Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions

scientific article published on 11 June 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

1 reference

based on heuristic

inferred from title

colon carcinoma

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based on heuristic

inferred from title

7

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Michel Chrétien

5

object named as

Chrétien M

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Europe PubMed Central

PubMed publication ID

25 November 2017

author name string

Khatib AM

1

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Siegfried G

2

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Prat A

3

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Luis J

4

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Metrakos P

6

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

language of work or name

0 references

publication date

11 June 2001

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Europe PubMed Central

PubMed publication ID

25 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

25 November 2017

276

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Europe PubMed Central

PubMed publication ID

25 November 2017

33

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Europe PubMed Central

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25 November 2017

30686-30693

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Eukaryotic protein processing: endoproteolysis of precursor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Proteolytic processing in the secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Processing of transforming growth factor beta 1 precursor by human furin convertase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Post-translational processing of the insulin-like growth factor-2 precursor. Analysis of O-glycosylation and endoproteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Post-translational processing of insulin-like growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a member of the subtilisin family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

From proopiomelanocortin to cancer. Possible role of convertases in neoplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Pro-protein convertase gene expression in human breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Proprotein-processing endoprotease furin decreases regulated secretory pathway-specific proteins in the pancreatic beta cell line MIN6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Proprotein-processing endoprotease furin controls the growth and differentiation of gastric surface mucous cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Proprotein-processing endoprotease furin controls growth of pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The IGF-I receptor in cancer research

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Enhanced invasion and liver colonization by lung carcinoma cells overexpressing the type 1 insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The insulin-like growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: a new avenue for breast cancer therapy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Deficient processing and activity of type I insulin-like growth factor receptor in the furin-deficient LoVo-C5 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Urokinase receptor and colorectal cancer survival.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Oncogenic activation of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Insulin-like-growth-factor-I (IGF-I) antagonizes apoptosis induced by serum deficiency and doxorubicin in neuronal cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Decreased phosphorylation of mutant insulin receptor by protein kinase C and protein kinase A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The insulin signalling system and the IRS proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Simultaneous production of IGF-I and EGF competing growth factors by HT-29 human colon cancer line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

The Pore-forming Toxin Proaerolysin Is Activated by Furin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Inhibition of processing of parathyroid hormone‐related peptide by anti‐sense furin: Effect in vitro and in vivo on rat leydig (H‐500) tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Blockade of the insulin-like growth-factor-I receptor inhibits growth of human colorectal cancer cells: evidence of a functional IGF-II-mediated autocrine loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Role of endoproteolytic processing in the adhesive and signaling functions of alphavbeta5 integrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Biological characterization and oncogene expression in human colorectal carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Vascular endothelial growth factor promotes cell-cycle transition from G0 to G1 phase in subcultured endothelial cells of diabetic rat thoracic aorta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101725200

21 January 2018

Specific Inhibition of Insulin-Like Growth Factor-1 and Insulin Receptor Tyrosine Kinase Activity and Biological Function by Tyrphostins

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M101725200

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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