(Q43641040)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519526%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease (English)

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4 February 2020

0 references

18

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4 February 2020

16

Rolf Bjerkvig

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4 February 2020

author name string

Pierre Garcia

1

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4 February 2020

Ihsen Youssef

2

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4 February 2020

Jo K Utvik

3

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4 February 2020

Sabrina Florent-Béchard

4

1 reference

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4 February 2020

Vanassa Barthélémy

5

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4 February 2020

Catherine Malaplate-Armand

6

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4 February 2020

Badreddine Kriem

7

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4 February 2020

Christophe Stenger

8

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4 February 2020

Violette Koziel

9

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4 February 2020

Jean-Luc Olivier

10

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4 February 2020

Marie-Christine Escanye

11

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4 February 2020

Marine Hanse

12

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4 February 2020

Ahmad Allouche

13

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4 February 2020

Cédric Desbène

14

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4 February 2020

Frances T Yen

15

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4 February 2020

Thierry Oster

17

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4 February 2020

Thierry Pillot

19

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4 February 2020

language of work or name

English

0 references

publication date

1 June 2010

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4 February 2020

published in

Journal of Neuroscience

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4 February 2020

volume

30

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4 February 2020

issue

22

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4 February 2020

page(s)

7516-7527

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Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?

4 February 2020

cites work

1 reference

12 December 2020

The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: involvement of its C-terminal fusogenic domain.

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Local endostatin treatment of gliomas administered by microencapsulated producer cells

1 reference

12 December 2020

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

12 December 2020

Nerve growth factor gene therapy for Alzheimer's disease

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

1 reference

12 December 2020

Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein

1 reference

12 December 2020

Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation

1 reference

12 December 2020

Role of neurotrophins in central synapse formation and stabilization.

1 reference

12 December 2020

Endogenous and exogenous ciliary neurotrophic factor enhances forebrain neurogenesis in adult mice

1 reference

12 December 2020

Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration

1 reference

12 December 2020

Ciliary neurotrophic factor: a role in obesity?

1 reference

12 December 2020

Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of amyloid-beta peptide

1 reference

12 December 2020

Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

1 reference

12 December 2020

Alzheimer disease: mechanistic understanding predicts novel therapies

1 reference

12 December 2020

Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons

1 reference

12 December 2020

Cytosolic phospholipase A2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid-beta peptide

1 reference

12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain

1 reference

12 December 2020

Neuroprotective strategies in Alzheimer's disease

1 reference

12 December 2020

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

1 reference

12 December 2020

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

1 reference

12 December 2020

Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease.

1 reference

12 December 2020

Neurorescue effects of VEGF on a rat model of Parkinson's disease

1 reference

12 December 2020

Microtubule-associated protein MAP1A, MAP1B, and MAP2 proteolysis during soluble amyloid beta-peptide-induced neuronal apoptosis. Synergistic involvement of calpain and caspase-3.

1 reference

12 December 2020

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

1 reference

12 December 2020

Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers

1 reference

12 December 2020

Clinical relevance of the neurotrophins and their receptors

1 reference

12 December 2020

Intracompartmental delivery of CNTF as therapy for Huntington's disease and retinitis pigmentosa

1 reference

12 December 2020

Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants

1 reference

12 December 2020

Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

1 reference

12 December 2020

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

1 reference

12 December 2020

Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis.

1 reference

12 December 2020

Therapeutic approaches to Alzheimer's disease

1 reference

12 December 2020

Neurotrophic factors in neurodegeneration.

1 reference

12 December 2020

Pathophysiological mechanisms for actions of the neurotrophins

1 reference

12 December 2020

N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis

1 reference

12 December 2020

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

1 reference

12 December 2020

Nerve growth factor gene therapy in Alzheimer disease

1 reference

12 December 2020

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

1 reference

12 December 2020

Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction

1 reference

12 December 2020

Progressive impairment in olfactory working memory in a mouse model of Mild Cognitive Impairment

1 reference

12 December 2020

Leptin increases adult hippocampal neurogenesis in vivo and in vitro

1 reference

12 December 2020

Transducible P11-CNTF rescues the learning and memory impairments induced by amyloid-beta peptide in mice.

1 reference

12 December 2020

Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease

1 reference

12 December 2020

Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice

1 reference

12 December 2020

Neurogenesis in the dentate gyrus depends on ciliary neurotrophic factor and signal transducer and activator of transcription 3 signaling.

1 reference

12 December 2020

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

12 December 2020

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

1 reference

12 December 2020

From neurotransmitters to neurotrophic factors to neurogenesis

1 reference

12 December 2020

Attenuation of scopolamine-induced impairment of spontaneous alteration behaviour by antagonist but not inverse agonist and agonist beta-carbolines

1 reference

12 December 2020

Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

12 December 2020

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Continued presence of intrastriatal but not intraventricular polymer-encapsulated PC12 cells is required for alleviation of behavioral deficits in Parkinsonian rodents

1 reference

12 December 2020

4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.

1 reference

12 December 2020

Targeted intraparenchymal delivery of human NGF by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition

1 reference

12 December 2020

10.1523/JNEUROSCI.4182-09.2010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519526%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

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4 February 2020

PubMed publication ID

20519526

1 reference