(Q43652164)

English

Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 November 2017

Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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author name string

L Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

T Himi

2

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Europe PubMed Central

PubMed publication ID

25 November 2017

I Morita

3

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

S Murota

4

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Europe PubMed Central

PubMed publication ID

25 November 2017

publication date

1 May 2001

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Europe PubMed Central

PubMed publication ID

25 November 2017

Cell Death & Differentiation

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Europe PubMed Central

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25 November 2017

8

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Europe PubMed Central

PubMed publication ID

25 November 2017

5

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Europe PubMed Central

PubMed publication ID

25 November 2017

528-536

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Europe PubMed Central

PubMed publication ID

25 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400838

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Apoptosis by death factor

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21 January 2018

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

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21 January 2018

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

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21 January 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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21 January 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

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21 January 2018

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

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21 January 2018

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

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21 January 2018

Cell death induction by TNF: a matter of self control

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21 January 2018

Molecular mechanisms of tumor necrosis factor-induced cytotoxicity. What we do understand and what we do not.

1 reference

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21 January 2018

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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21 January 2018

Inhibition of TNF-induced apoptosis by NF-kappa B.

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21 January 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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21 January 2018

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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21 January 2018

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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21 January 2018

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

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21 January 2018

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

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21 January 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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21 January 2018

Cellular survival: a play in three Akts

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21 January 2018

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

1 reference

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21 January 2018

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

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21 January 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

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21 January 2018

IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase

1 reference

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21 January 2018

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

1 reference

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21 January 2018

Mitochondrial control of cell death

1 reference

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21 January 2018

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

1 reference

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21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

1 reference

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21 January 2018

Phosphorylation of Raf by ceramide-activated protein kinase

1 reference

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21 January 2018

Tumor necrosis factor promotes phosphorylation and binding of insulin receptor substrate 1 to phosphatidylinositol 3-kinase in 3T3-L1 adipocytes

1 reference

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21 January 2018

A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

Injected cytochrome c induces apoptosis

1 reference

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21 January 2018

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

21 January 2018

TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

7 January 2021

based on heuristic

inferred from DOI database lookup

The central executioners of apoptosis: caspases or mitochondria?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to TNF-alpha cytotoxicity can be achieved through different signaling pathways in rat mesangial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400838

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4400838

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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