(Q43663394)

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Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis

scientific article published in June 2001

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scholarly article

1 reference

Europe PubMed Central

25 November 2017

Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis (English)

1 reference

Europe PubMed Central

25 November 2017

Yoshihisa Matsumoto

2

1 reference

Europe PubMed Central

25 November 2017

author name string

Mori N

1

1 reference

Europe PubMed Central

25 November 2017

Okumoto M

3

1 reference

Europe PubMed Central

25 November 2017

Suzuki N

4

1 reference

Europe PubMed Central

25 November 2017

Yamate J

5

1 reference

Europe PubMed Central

25 November 2017

language of work or name

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publication date

1 June 2001

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Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

20

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Europe PubMed Central

25 November 2017

28

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Europe PubMed Central

25 November 2017

3609-3619

1 reference

Europe PubMed Central

25 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204497

0 references

Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

1 reference

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

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Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

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Recombinant congenic strains--a new tool for analyzing genetic traits determined by more than one gene

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DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

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DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

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Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination

1 reference

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Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis

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Unexpected effects of the severe combined immunodeficiency mutation on murine lymphomagenesis

1 reference

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Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus

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Genetic analysis of susceptibility to radiation-induced apoptosis of thymocytes in mice

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Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

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A review of dsb induction data for varying quality radiations

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The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice

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Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

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Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

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Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents

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A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

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Limiting dilution analysis of T-cell progenitors in the bone marrow of thymic lymphoma-susceptible B10 and -resistant C3H mice after fractionated whole-body X-irradiation

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Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.

1 reference

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A gel-electrophoretic analysis for improved sensitivity and specificity of DNA-dependent protein kinase activity

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Cleavage and phosphorylation of XRCC4 protein induced by X-irradiation

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Strain Difference in the Susceptibility of Thymocytes to Radiation-induced Apoptosis: In Vitro Study

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Genetic dissection of susceptibility to radiation-induced apoptosis of thymocytes and mapping of Rapop1, a novel susceptibility gene

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Genetics of susceptibility to radiation-induced apoptosis in colon: two loci on Chromosomes 9 and 16

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Resistance of STS/A mice to lymphoma induction by X-irradiation

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7 January 2021

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Radiation-induced lymphomas in MSM, (BALB/cHeA x MSM) F1 and (BALB/cHeA x STS/A) F1 hybrid mice

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Genetic composition of the recombinant congenic strains

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Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

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Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

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Radiation-induced interphase death of rat thymocytes is internally programmed (apoptosis)

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10.1038/SJ.ONC.1204497

1 reference

Europe PubMed Central

25 November 2017

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1 reference

Europe PubMed Central

25 November 2017

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