(Q43668389)

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Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit

scientific article published on 9 July 2001

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Europe PubMed Central

PubMed publication ID

25 November 2017

Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

author name string

Brodt P

1

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Europe PubMed Central

PubMed publication ID

25 November 2017

Fallavollita L

2

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Europe PubMed Central

PubMed publication ID

25 November 2017

Khatib AM

3

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Samani AA

4

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Europe PubMed Central

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25 November 2017

Zhang D

5

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Europe PubMed Central

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25 November 2017

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publication date

9 July 2001

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25 November 2017

Journal of Biological Chemistry

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25 November 2017

276

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Europe PubMed Central

PubMed publication ID

25 November 2017

36

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

33608-33615

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

Integrins, oncogenes, and anchorage independence.

1 reference

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Bidirectional signaling between the cytoskeleton and integrins

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Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic

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Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor

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The role of the IGF-I receptor in the growth and transformation of mammalian cells.

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

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Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells

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Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth

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21 January 2018

Controlling IGF-receptor function: a possible strategy for tumor therapy

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Enhanced invasion and liver colonization by lung carcinoma cells overexpressing the type 1 insulin-like growth factor receptor

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Different Effects on Mitogenesis and Transformation of a Mutation at Tyrosine 1251 of the Insulin-like Growth Factor I Receptor

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The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis

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21 January 2018

Mutant IGF-I Receptors as Dominant Negatives for Growth and Transformation

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Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis

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Differences in the repertoires of basement membrane degrading enzymes in two carcinoma sublines with distinct patterns of site-selective metastasis.

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

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Insulin-like growth factor-I: specific binding to high and low affinity sites and mitogenic action throughout the life span of WI-38 cells

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21 January 2018

Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor

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21 January 2018

Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

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21 January 2018

Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth

1 reference

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21 January 2018

Immunogold localization of beta 1-integrin in bone: effect of glucocorticoids and insulin-like growth factor I on integrins and osteocyte formation.

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21 January 2018

Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98

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21 January 2018

Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor

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21 January 2018

Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

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21 January 2018

Signal transduction by beta1 integrin receptors in human chondrocytes in vitro: collaboration with the insulin-like growth factor-I receptor

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21 January 2018

Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)

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21 January 2018

p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors

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21 January 2018

Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction

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21 January 2018

Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology

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21 January 2018

Insulin-like growth factor I stimulates tyrosine phosphorylation of p130(Cas), focal adhesion kinase, and paxillin. Role of phosphatidylinositol 3'-kinase and formation of a p130(Cas).Crk complex

1 reference

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21 January 2018

In vivo regulation of CrkII and CrkL proto-oncogenes in the uterus by insulin-like growth factor-I. Differential effects on tyrosine phosphorylation and association with paxillin

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways

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Insulin-like growth factors and cancer

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A practical computer-based approach to the analysis of radioligand binding experiments

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Integrin alpha3beta1 can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma

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21 January 2018

Identifiers

10.1074/JBC.M102754200

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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