(Q43686523)

25 November 2017

title

The TGF-β-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells (English)

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25 November 2017

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9

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25 November 2017

J-S Delisle

1

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25 November 2017

M Giroux

2

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25 November 2017

G Boucher

3

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25 November 2017

J-R Landry

4

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25 November 2017

M-P Hardy

5

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25 November 2017

S Lemieux

6

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25 November 2017

R G Jones

7

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25 November 2017

B T Wilhelm

8

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25 November 2017

publication date

17 January 2013

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25 November 2017

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25 November 2017

volume

14

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25 November 2017

issue

2

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25 November 2017

page(s)

115-126

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https://scigraph.springernature.com/pub.10.1038/gene.2012.63

25 November 2017

exact match

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cites work

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Transforming growth factor-beta regulation of immune responses

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

TGF-beta: a master of all T cell trades

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Specificity and versatility in tgf-beta signaling through Smads

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

TGF-β signaling in T cells: roles in lymphoid and epithelial neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

T cell activation leads to protein kinase C theta-dependent inhibition of TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Characterization of murine cathepsin W and its role in cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Revving the engine: signal transduction fuels T cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

mTOR regulates memory CD8 T-cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Regulation and function of mTOR signalling in T cell fate decisions

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Regulation of immune responses by mTOR.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Fuel feeds function: energy metabolism and the T-cell response

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Anergic T cells are metabolically anergic

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Metabolic pathways in T cell fate and function

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

mTOR at the crossroads of T cell proliferation and tolerance

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Distinct effects of TGF-beta 1 on CD4+ and CD8+ T cell survival, division, and IL-2 production: a role for T cell intrinsic Smad3

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Prediction of graft-versus-host disease in humans by donor gene-expression profiling

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Antagonistic Smad transcription factors control the dauer/non-dauer switch in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Essential role of TGF-beta signaling in glucose-induced cell hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Smad2 and 3 transcription factors control muscle mass in adulthood.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

FOXO transcription factors throughout T cell biology

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Asynchronous differentiation of CD8 T cells that recognize dominant and cryptic antigens

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

TM4: a free, open-source system for microarray data management and analysis

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2012.63

7 January 2021

Identifiers

DOI

10.1038/GENE.2012.63

1 reference

Dimensions Publication ID

25 November 2017

1040487274

0 references

1 reference