(Q43737962)

26 November 2017

title

Inhibition of geranylgeranylation blocks agonist-induced actin reorganization in human airway smooth muscle cells (English)

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26 November 2017

Lesh RE

1

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26 November 2017

Emala CW

2

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26 November 2017

Lee HT

3

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26 November 2017

Zhu D

4

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26 November 2017

Panettieri RA

5

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26 November 2017

Hirshman CA

6

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26 November 2017

publication date

1 October 2001

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American Journal of Physiology - Lung Cellular and Molecular Physiology

26 November 2017

published in

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26 November 2017

volume

281

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26 November 2017

issue

4

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26 November 2017

page(s)

L824-31

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RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

CAAX geranylgeranyl transferase transfers farnesyl as efficiently as geranylgeranyl to RhoB

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Mechanisms of protein prenylation and role in G protein function

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Enzymatic modification of proteins with a geranylgeranyl isoprenoid

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Augmented acetylcholine-induced, Rho-mediated Ca2+ sensitization of bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor

21 January 2018

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The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Inhibition of RhoA translocation and calcium sensitization by in vivo ADP-ribosylation with the chimeric toxin DC3B

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Small GTP-binding proteins and the regulation of the actin cytoskeleton

21 January 2018

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Role of Rho family proteins in phospholipase D activation by growth factors

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Simultaneous localization and quantification of relative G and F actin content: optimization of fluorescence labeling methods

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

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Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Effect of cytochalasins on F-actin and morphology of Ehrlich ascites tumor cells.

21 January 2018

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Role of isoprenoid lipids on the heterotrimeric G protein gamma subunit in determining effector activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Newly synthesized Rho A, not Ras, is isoprenylated and translocated to membranes coincident with progression of the G1 to S phase of growth-stimulated rat FRTL-5 cells

21 January 2018

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Microinjection of recombinant p21rho induces rapid changes in cell morphology

21 January 2018

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Quantitative changes in cytoskeletal and nuclear actins during cellular transformation

21 January 2018

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Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes

21 January 2018

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Rho: theme and variations

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Inhibition of Ras prenylation: a novel approach to cancer chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Control of actin polymerization in live and permeabilized fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Rho GTPases and signaling networks

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

Actin reorganization in airway smooth muscle cells involves Gq and Gi-2 activation of Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.2001.281.4.L824

10.1152/AJPLUNG.2001.281.4.L824

21 January 2018

Identifiers

DOI

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1 reference