(Q43743125)

26 November 2017

The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies (English)

1 reference

26 November 2017

1 reference

Martello LA

1

1 reference

26 November 2017

LaMarche MJ

2

1 reference

26 November 2017

He L

3

1 reference

26 November 2017

Beauchamp TJ

4

1 reference

26 November 2017

Smith AB

5

1 reference

26 November 2017

Horwitz SB

6

1 reference

26 November 2017

1 September 2001

1 reference

26 November 2017

Chemistry and Biology

1 reference

26 November 2017

8

1 reference

26 November 2017

843-855

1 reference

26 November 2017

9

1 reference

THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS

26 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Promotion of microtubule assembly in vitro by taxol

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Taxol stabilizes microtubules in mouse fibroblast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Substoichiometric binding of taxol suppresses microtubule dynamics.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Eleutherobin, a New Cytotoxin that Mimics Paclitaxel (Taxol) by Stabilizing Microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A common pharmacophore for cytotoxic natural products that stabilize microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Immunosuppression by discodermolide.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Gram-scale synthesis of (+)-discodermolide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Chemical Biology of Epothilones

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Structure-activity profiles of eleutherobin analogs and their cross-resistance in Taxol-resistant cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Sulfur trioxide in the oxidation of alcohols by dimethyl sulfoxide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A FACILE CLEAVAGE OF BENZYLIDENE ACETALS WITH DIISOBUTYLALUMINUM HYDRIDE

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Solution structure of (+)-discodermolide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Characterization of the Taxol Binding Site on the Microtubule

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

High-resolution model of the microtubule

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Microtubule Assembly in the Absence of Added Nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Structure of the alpha beta tubulin dimer by electron crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Crystal and molecular structure of paclitaxel (taxol).

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2801%2900055-2

7 January 2021

10.1016/S1074-5521(01)00055-2

Identifiers

DOI

1 reference

26 November 2017

1 reference