(Q43777035)

30 June 2018

title

High expression of thymidylate synthase leads to resistance to 5-fluorouracil in biliary tract carcinoma in vitro (English)

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30 June 2018

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K Habara

1

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30 June 2018

T Ajiki

2

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30 June 2018

T Kamigaki

3

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30 June 2018

T Nakamura

4

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30 June 2018

Y Kuroda

5

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30 June 2018

publication date

1 October 2001

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30 June 2018

number of pages

6

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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30 June 2018

volume

92

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30 June 2018

issue

10

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30 June 2018

page(s)

1127-1132

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30 June 2018

Radiosensitivity of human biliary tract cancer cell lines in vitro

cites work

1 reference

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Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

3 July 2018

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Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil.

3 July 2018

1 reference

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Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.

3 July 2018

1 reference

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A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance

3 July 2018

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A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

3 July 2018

1 reference

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Perihilar cholangiocarcinoma. Postoperative radiotherapy does not improve survival

3 July 2018

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Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity.

3 July 2018

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Thymidylate synthase and drug resistance

3 July 2018

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

3 July 2018

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Biliary adenocarcinoma. Characterisation of three new human tumor cell lines.

3 July 2018

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Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile

3 July 2018

1 reference

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Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity

3 July 2018

1 reference

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[Establishment and characterization of a human gall bladder carcinoma cell line NOZ].

3 July 2018

1 reference

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Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells

3 July 2018

1 reference

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Clinical pharmacology of 5-fluorouracil

3 July 2018

1 reference

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Biochemical pharmacology and analysis of fluoropyrimidines alone and in combination with modulators

3 July 2018

1 reference

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Metabolism and mechanism of action of 5-fluorouracil

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

Preparation of the antibodies against recombinant human thymidylate synthase for the detection of its intratumoral levels and the application to sensitivity-study of 5-fluorouracil.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

Immunohistochemical evaluation of thymidylate synthase in gastric carcinoma using a new polyclonal antibody: the clinical role of thymidylate synthase as a prognostic indicator and its therapeutic usefulness.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926613

Thymidylate synthase is a predictor for response and resistance in hepatic artery infusion chemotherapy

15 August 2018

1 reference

12 December 2020

Hepatic artery infusion of 5-fluorouracil and mitomycin C in cholangiocarcinoma and gallbladder carcinoma

1 reference

12 December 2020

Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infus

1 reference

12 December 2020

5-Fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract

1 reference

12 December 2020

10.1111/J.1349-7006.2001.TB01068.X

Identifiers

DOI

1 reference

30 June 2018

PMCID

5926613

1 reference

30 June 2018

PubMed ID

11676864

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30 June 2018