(Q43819965)

English

Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.

scientific article published in December 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 November 2017

Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

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phosphorylation

1 reference

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author name string

R D Peavy

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

M S Chang

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

E Sanders-Bush

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

P J Conn

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

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publication date

1 December 2001

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

9619-9628

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist- and reflex-evoked internalization of metabotropic glutamate receptor 5 in enteric neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor signal transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-protein-independent signaling mediated by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and functions of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural organization of the mouse metabotropic glutamate receptor subtype 3 gene and its regulation by growth factors in cultured cortical astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutamate receptor ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of lysophosphatidic acid on striatal astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of phosphoinositide hydrolysis by trans-(+/-)-ACPD is greatly enhanced when astrocytes are cultured in a serum-free defined medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heptahelical receptor signaling: beyond the G protein paradigm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bradykinin B(2) receptor-mediated mitogen-activated protein kinase activation in COS-7 cells requires dual signaling via both protein kinase C pathway and epidermal growth factor receptor transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate induces the growth factors NGF, bFGF, the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein-coupled receptor kinase-mediated desensitization of metabotropic glutamate receptor 1A protects against cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No role for Ca++ or protein kinase C in alpha-1A adrenergic receptor activation of mitogen-activated protein kinase pathways in transfected PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internalization of G protein-coupled receptors in single olfactory receptor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor agonists increase expression of glutamate transporter GLT-1 in astrocytes through pathways dependent on phosphatidylinositol 3-kinase and transcription factor NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization and neurotransmitters increase neuronal protein tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for transforming growth factor alpha as an inducer of astrogliosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the binding site for Gqalpha on its effector Bruton's tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src tyrosine kinase is a novel direct effector of G proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-stimulated activation of DNA synthesis via mitogen-activated protein kinase in primary astrocytes: involvement of protein kinase C and related adhesion focal tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional expression and regulation of alternative forms of mRNAs derived from two distinct transcription initiation sites of the rat mGluR5 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-24-09619.2001

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6763045&resulttype=core&format=json

12 May 2020

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