(Q43824389)

27 November 2017

Lck plays a critical role in Ca(2+) mobilization and CD28 costimulation in mature primary T cells (English)

1 reference

27 November 2017

Trobridge PA

1

1 reference

PubMed ID

11745376

27 November 2017

Levin SD

series ordinal

2

1 reference

PubMed ID

11745376

27 November 2017

language of work or name

English

0 references

publication date

1 December 2001

1 reference

European Journal of Immunology

27 November 2017

1 reference

27 November 2017

31

1 reference

27 November 2017

12

1 reference

27 November 2017

3567-3579

1 reference

Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line

27 November 2017

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Profound block in thymocyte development in mice lacking p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Delayed thymocyte development induced by augmented expression of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Thymic tumorigenesis induced by overexpression of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Functional dissection of the lck proximal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Lck activity controls CD4/CD8 T cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

CD28/B7 system of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Molecular requirements for lineage commitment in the thymus--antibody-mediated receptor engagements reveal a central role for lck in lineage decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

A kinase-independent function of Lck in potentiating antigen-specific T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Differential signaling by lymphocyte antigen receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Long-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Fyn can partially substitute for Lck in T lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1521-4141%28200112%2931%3A12%3C3567%3A%3AAID-IMMU3567%3E3.0.CO%3B2-M

10.1002/1521-4141(200112)31:12<3567::AID-IMMU3567>3.0.CO;2-M

21 January 2018

Identifiers

DOI

1 reference

27 November 2017

1 reference

PubMed ID

11745376