(Q43830944)

27 November 2017

title

The clinical relevance of plasma protein binding changes (English)

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27 November 2017

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27 November 2017

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27 November 2017

Jeffrey Lipman

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language of work or name

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1 January 2013

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Clinical Pharmacokinetics

27 November 2017

published in

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27 November 2017

volume

52

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27 November 2017

issue

1

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27 November 2017

page(s)

1-8

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Hypoalbuminemia in critically ill patients with cancer: incidence and mortality.

27 November 2017

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The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients

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Antibiotic tissue penetration and its relevance: impact of tissue penetration on infection response

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Pharmacokinetics and pharmacodynamics of sequential intravenous and subcutaneous teicoplanin in critically ill patients without vasopressors

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Effects of concentration-dependent plasma protein binding on ceftriaxone kinetics.

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Determinants of carbamazepine and carbamazepine 10,11-epoxide binding to serum protein, albumin and alpha 1-acid glycoprotein

21 January 2018

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Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics

21 January 2018

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Pharmacokinetics of once-daily dosing of ertapenem in critically ill patients with severe sepsis

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The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery

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The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients

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Therapeutic drug monitoring-guided high teicoplanin dosage regimen required to treat a hypoalbuminemic renal transplant patient undergoing continuous venovenous hemofiltration

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Effects of pH on Protein Binding of Lidocaine

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The pH dependency of the binding of drugs to plasma proteins in man.

21 January 2018

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Changes in plasma protein binding have little clinical relevance

21 January 2018

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Plasma protein binding displacement interactions--why are they still regarded as clinically important?

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What is the True Clinical Significance of Plasma Protein Binding Displacement Interactions?

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Pharmacokinetics of aztreonam in patients with gram-negative infections

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Pharmacokinetic evaluation of single-dose intravenous daptomycin in patients with thermal burn injury

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Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers

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Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin

21 January 2018

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Pharmacokinetics of intravenous fusidic acid in patients with cholestasis

21 January 2018

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Teicoplanin pharmacokinetics in healthy volunteers after administration of intravenous loading and maintenance doses

21 January 2018

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Hypoalbuminemia as a risk factor for over-anticoagulation

21 January 2018

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Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection

21 January 2018

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Augmented renal clearance in the Intensive Care Unit: an illustrative case series

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Augmented renal clearance: implications for antibacterial dosing in the critically ill.

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Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept

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Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability

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Using PK/PD to optimize antibiotic dosing for critically ill patients

21 January 2018

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Antibacterial dosing in intensive care: pharmacokinetics, degree of disease and pharmacodynamics of sepsis

21 January 2018

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Antibiotic dosing in multiple organ dysfunction syndrome

21 January 2018

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Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock

21 January 2018

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Clinical relevance of pharmacokinetics and pharmacodynamics in cardiac critical care patients

21 January 2018

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Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review

21 January 2018

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Diseases and Drug Protein Binding

21 January 2018

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The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

21 January 2018

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12 December 2020

Pharmacokinetics of sodium fusidate after single and repeated infusions and oral administration of a new formulation

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12 December 2020

Pharmacokinetics of the monobactam SQ 26,776 after single intravenous doses in healthy subjects

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12 December 2020

Subtherapeutic Initial β-Lactam Concentrations in Select Critically Ill Patients

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12 December 2020

Free drug fraction vs free drug concentration: a matter of frequent confusion

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12 December 2020

Plasma protein binding may reduce antimicrobial activity by preventing intra-bacterial uptake of antibiotics, for example clindamycin

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12 December 2020

Impact of pH on plasma protein binding in equilibrium dialysis

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12 December 2020

Propranolol binding in serum: comparison of methods and investigation of effects of drug concentration, pH, and temperature

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12 December 2020

What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance

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12 December 2020

10.1007/S40262-012-0018-5

Identifiers

DOI

1 reference

Dimensions Publication ID

27 November 2017

1026024203

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