(Q43879780)

27 November 2017

title

DNA double-strand breaks and ATM activation by transcription-blocking DNA lesions (English)

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27 November 2017

4

Yves Pommier

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27 November 2017

Olivier Sordet

1

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27 November 2017

Asako J Nakamura

series ordinal

2

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27 November 2017

Christophe E Redon

series ordinal

3

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27 November 2017

publication date

2 January 2010

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27 November 2017

number of pages

5

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inferred from page(s)

published in

Cell Cycle

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27 November 2017

volume

9

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27 November 2017

issue

2

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27 November 2017

page(s)

274-278

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Cellular roles of dna topoisomerases: a molecular perspective

27 November 2017

cites work

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12 December 2020

Repair of topoisomerase I-mediated DNA damage

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12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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12 December 2020

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

1 reference

12 December 2020

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

1 reference

12 December 2020

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

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12 December 2020

The problem of hypernegative supercoiling and R-loop formation in transcription

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12 December 2020

Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

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12 December 2020

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

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12 December 2020

Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability

1 reference

12 December 2020

Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.

1 reference

12 December 2020

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

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12 December 2020

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

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12 December 2020

Topoisomerase I inhibitors: camptothecins and beyond

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12 December 2020

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12 December 2020

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

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12 December 2020

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

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12 December 2020

Transcription - guarding the genome by sensing DNA damage

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12 December 2020

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

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12 December 2020

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

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12 December 2020

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

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12 December 2020

Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes

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12 December 2020

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

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12 December 2020

DNA topoisomerase I-mediated nicking of circular duplex DNA.

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12 December 2020

A mechanism of formation of a persistent hybrid between elongating RNA and template DNA

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12 December 2020

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

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12 December 2020

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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12 December 2020

Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PK

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12 December 2020

Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex

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12 December 2020

The ATM-mediated DNA-damage response: taking shape.

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12 December 2020

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

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12 December 2020

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

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12 December 2020

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

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12 December 2020

Mechanism of R-loop formation at immunoglobulin class switch sequences

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12 December 2020

Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

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12 December 2020

Ataxia telangiectasia-mutated protein can regulate p53 and neuronal death independent of Chk2 in response to DNA damage.

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12 December 2020

DNA-damage response, survival and differentiation in vitro of a human neural stem cell line in relation to ATM expression.

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12 December 2020

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

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12 December 2020

Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in Mammalian cells lacking topoisomerase I.

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12 December 2020

Topoisomerase I-mediated DNA damage

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12 December 2020

The effects of camptothecin on RNA polymerase II transcription: roles of DNA topoisomerase I.

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12 December 2020

Phosphorylation of Sp1 in response to DNA damage by ataxia telangiectasia-mutated kinase

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12 December 2020

Properties of a primer RNA-DNA hybrid at the mouse mitochondrial DNA leading-strand origin of replication

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12 December 2020

Repair of and checkpoint response to topoisomerase I-mediated DNA damage

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12 December 2020

The ATR-p53 pathway is suppressed in noncycling normal and malignant lymphocytes

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12 December 2020

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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12 December 2020

Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity

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12 December 2020

DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1alpha gene locus

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12 December 2020

Mechanism and regulation of human non-homologous DNA end-joining

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12 December 2020

Identifiers

DOI

10.4161/CC.9.2.10506

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27 November 2017

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