(Q43908763)

28 November 2017

title

Irofulven induces apoptosis in breast cancer cells regardless of caspase-3 status (English)

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28 November 2017

Maryanne C S Herzig

1

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28 November 2017

Huiyun Liang

2

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28 November 2017

Anne E Johnson

3

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28 November 2017

Barbara Woynarowska

4

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28 November 2017

Jan M Woynarowski

5

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28 November 2017

language of work or name

English

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publication date

1 January 2002

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Breast Cancer Research and Treatment

28 November 2017

published in

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28 November 2017

volume

71

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28 November 2017

issue

2

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28 November 2017

page(s)

133-143

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https://scigraph.springernature.com/pub.10.1023/a:1013855615712

28 November 2017

exact match

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cites work

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Induction of apoptosis by cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Catalytic properties of the caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Mechanisms mediating caspase activation in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Pro-caspase-3 is a major physiologic target of caspase-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies.

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1013855615712

MGI 114: augmentation of antitumor activity when combined with topotecan.

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Anti-leukemic action of the novel agent MGI 114 (HMAF) and synergistic action with topotecan

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft.

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Differentiation and assessment of cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

21 January 2018

1 reference

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Deciphering the pathways of life and death

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1013855615712

A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

Apoptosis and metastasis: increased apoptosis resistance of metastatic cancer cells is associated with the profound deficiency of apoptosis execution mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Apoptosis in favourable neuroblastomas is not dependent on Fas (CD95/APO-1) expression but on activated caspase 3 (CPP32)

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Caspase-dependent and -independent events in apoptosis induced by hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114)

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF)

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Targeting apoptosis by hydroxymethylacylfulvene in combination with gamma radiation in prostate tumor cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase path

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

An interleukin-1 beta-converting enzyme-like protease is a common mediator of apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Redox regulation of the caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

1 reference

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1013855615712

7 January 2021

Identifiers

DOI

10.1023/A:1013855615712

1 reference

Dimensions Publication ID

28 November 2017

1053473551

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1 reference