(Q43908844)

28 November 2017

title

Influence of the structure of drug moieties on the in vitro efficacy of HPMA copolymer-geldanamycin derivative conjugates (English)

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28 November 2017

Yuji Kasuya

1

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28 November 2017

Zheng-Rong Lu

2

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28 November 2017

Pavla Kopecková

3

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28 November 2017

S Esmail Tabibi

4

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28 November 2017

Jindrich Kopecek

5

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28 November 2017

publication date

1 February 2002

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28 November 2017

published in

Pharmaceutical Research

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28 November 2017

volume

19

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28 November 2017

issue

2

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28 November 2017

page(s)

115-123

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HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line

28 November 2017

cites work

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12 December 2020

High-molecular weight HPMA copolymer-adriamycin conjugates

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12 December 2020

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S-S bridges of cathepsin B and H from bovine spleen: a basis for cathepsin B model building and possible functional implications for discrimination between exo- and endopeptidase activities among cathepsins B, H and L

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A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

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12 December 2020

The Hsp90 complex--a super-chaperone machine as a novel drug target

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12 December 2020

Metabolite efflux and influx across the lysosome membrane.

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12 December 2020

Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters. Commentary re: P. Münster et al., Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an

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12 December 2020

Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers

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12 December 2020

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

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12 December 2020

Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines

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12 December 2020

The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide

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12 December 2020

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

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12 December 2020

Sterically stabilized liposomes

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12 December 2020

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

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12 December 2020

Physicochemical surface properties and phagocytosis by polymorphonuclear leucocytes of different serogroups of Salmonella.

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12 December 2020

Electrostatic interaction of microcapsules with guinea-pig polymorphonuclear leucocytes.

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12 December 2020

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

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12 December 2020

Improved synthesis and evaluation of 17-substituted aminoalkylgeldanamycin derivatives applicable to drug delivery systems

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12 December 2020

Synthesis and evaluation of antiproliferative activity of a geldanamycin-Herceptin immunoconjugate

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12 December 2020

Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: studies with poly(ethylene glycol)-coated vesicles

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12 December 2020

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

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12 December 2020

Comparison of the anticancer effect of free and HPMA copolymer-bound adriamycin in human ovarian carcinoma cells.

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12 December 2020

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

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12 December 2020

Synthesis and characterization of HPMA copolymer-aminopropylgeldanamycin conjugates

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12 December 2020

Identifiers

DOI

10.1023/A:1014216712820

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28 November 2017

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