(Q43946534)

28 November 2017

title

Relative importance of maternal and embryonic microsomal epoxide hydrolase in 7,12-dimethylbenz[a]anthracene-induced developmental toxicity (English)

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28 November 2017

Masaaki Miyata

1

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28 November 2017

Kazuko Motoki

2

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28 November 2017

Etsuko Tamura

3

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28 November 2017

Masayuki Furukawa

4

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28 November 2017

Frank J Gonzalez

5

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28 November 2017

Yasushi Yamazoe

6

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28 November 2017

language of work or name

English

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publication date

1 March 2002

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28 November 2017

published in

Biochemical Pharmacology

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28 November 2017

volume

63

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28 November 2017

issue

6

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28 November 2017

page(s)

1077-1084

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Cytochrome-P450-dependent biotransformation of xenobiotics in human and rodent embryonic tissues.

28 November 2017

cites work

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7 January 2021

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Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis

7 January 2021

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How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress

7 January 2021

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Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic Compounds

7 January 2021

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The apparent ubiquity of epoxide hydratase in rat organs

7 January 2021

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Expression of P450 isoenzymes during rat liver organogenesis

7 January 2021

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Quantitative estimation of catechol/methylcatechol pathways in human phenytoin metabolism

7 January 2021

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Prenatal prediction of risk of the fetal hydantoin syndrome

7 January 2021

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Additional evidence for the involvement of the 3,4-diol 1,2-oxides in the metabolic activation of 7,12-dimethylbenz[a]anthracene in mouse skin

7 January 2021

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Identification of four trans-3,4-dihydrodiol metabolites of 7,12-dimethylbenz[a]anthracene and their in vitro DNA-binding activities upon further metabolism

7 January 2021

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Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

7 January 2021

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Genetically mediated induction of drug-metabolizing enzymes associated with congenital defects in the mouse

7 January 2021

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Epoxide hydratase: sex specific expression and rate-limiting role in DMBA metabolism

7 January 2021

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Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2

7 January 2021

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Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

7 January 2021

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Mechanism of 7,12-dimethylbenz[a]anthracene-induced immunotoxicity: role of metabolic activation at the target organ

7 January 2021

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The role of secondary metabolism in the metabolic activation of 7,12-dimethylbenz[a]anthracene by rat liver microsomes.

7 January 2021

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Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation

7 January 2021

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A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene.

7 January 2021

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7,12-Dimethylbenz[a]anthracene activates protein-tyrosine kinases Fyn and Lck in the HPB-ALL human T-cell line and increases tyrosine phosphorylation of phospholipase C-gamma 1, formation of inositol 1,4,5-trisphosphate, and mobilization of intracel

7 January 2021

1 reference

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Persistence of calcium elevation in the HPB-ALL human T cell line correlates with immunosuppressive properties of polycyclic aromatic hydrocarbons

7 January 2021

1 reference

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Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900847-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(02)00847-X

1 reference

28 November 2017

1 reference