(Q44010945)

28 November 2017

2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells (English)

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28 November 2017

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Suparna Qanungo

1

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28 November 2017

Aruna Basu

series ordinal

2

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28 November 2017

Madhusudan Das

series ordinal

3

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28 November 2017

Subrata Haldar

series ordinal

4

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28 November 2017

language of work or name

English

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publication date

1 June 2002

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28 November 2017

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28 November 2017

21

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28 November 2017

4149-4157

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28 November 2017

26

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205508

28 November 2017

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cites work

Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

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Death receptors: signaling and modulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

2-Methoxyestradiol-induced phosphorylation of Bcl-2: uncoupling from JNK/SAPK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Inactivation of Bcl-2 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Oral administration of an estrogen metabolite-induced potentiation of radiation antitumor effects in presence of wild-type p53 in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Cellular tumorigenicity in nude mice. Test of associations among loss of cell-surface fibronectin, anchorage independence, and tumor-forming ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Breaking the mitochondrial barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Impact of Continuously Administered Catechol Estrogens on Uterine Growth and Luteinizing Hormone Secretion*

21 January 2018

1 reference

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2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

The mammalian metabolite, 2-methoxyestradiol, affects P53 levels and apoptosis induction in transformed cells but not in normal cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Inhibition of angiogenesis induces chromaffin differentiation and apoptosis in neuroblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Angiostatic treatment of neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

The mitochondrion in apoptosis: how Pandora's box opens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

The effect of milk and sucrose consumption on caries in 6-to-11-year-old Italian schoolchildren

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

The cell cycle and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Apoptosis in hormone-responsive malignancies.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

17beta-Estradiol metabolites affect some regulators of the MCF-7 cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Activation of caspases triggered by cytochrome c in vitro

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Cell Death in Development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205508

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205508

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release_nhmh5dkrazffpfsaq5c3nj2ka4

28 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/nhmh5dkrazffpfsaq5c3nj2ka4

24 November 2022

mapped directly with Wikidata item

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