(Q44031795)

29 November 2017

Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein (English)

1 reference

29 November 2017

0 references

3

Moussa B H Youdim

1 reference

29 November 2017

Yael Avramovich

1

1 reference

PubMed ID

12070143

29 November 2017

Tamar Amit

series ordinal

2

1 reference

PubMed ID

12070143

29 November 2017

language of work or name

English

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publication date

17 June 2002

1 reference

Journal of Biological Chemistry

29 November 2017

1 reference

29 November 2017

277

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29 November 2017

35

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29 November 2017

31466-31473

1 reference

Amyloid beta-protein and the genetics of Alzheimer's disease

29 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Amyloid, the presenilins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

A portrait of Alzheimer secretases--new features and familiar faces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Regulation of amyloid precursor protein cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Inflammation and Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Glial fibrillary acidic protein and Alzheimer-type senile dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Localization and cell association of C1q in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Risk of Alzheimer's disease and duration of NSAID use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Arachidonate metabolites affect the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Involvement of amyloid precursor protein in functional synapse formation in cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

beta-Amyloid formation as a potential therapeutic target for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Processing of tumour necrosis factor-α precursor by metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

General and dramatic glial reaction in Alzheimer brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

β-AMYLOID FRAGMENT POTENTIATES IL-6 AND TNF-α SECRETION BY LPS IN ASTROCYTES BUT NOT IN MICROGLIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

beta-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Activity of alpha-secretase as the common final effector of protein kinase C-dependent and -independent modulation of amyloid precursor protein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201308200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201308200

1 reference

29 November 2017

1 reference

PubMed ID

12070143