(Q44107294)

29 November 2017

Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects (English)

1 reference

29 November 2017

1 reference

7

1 reference

29 November 2017

6

Torgeir Flatmark

1 reference

29 November 2017

Frederico Faria Miranda

1

1 reference

29 November 2017

Knut Teigen

2

1 reference

29 November 2017

Matthías Thórólfsson

3

1 reference

29 November 2017

Randi M Svebak

4

1 reference

29 November 2017

Per M Knappskog

5

1 reference

29 November 2017

language of work or name

English

0 references

publication date

15 August 2002

1 reference

Journal of Biological Chemistry

29 November 2017

7

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

29 November 2017

277

1 reference

29 November 2017

43

1 reference

29 November 2017

40937-40943

1 reference

Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms

29 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

The hyperphenylalaninemias of man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

The structural basis of phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Structural basis of autoregulation of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Regulation of the activity of hepatic phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylation of recombinant human phenylalanine hydroxylase: effect on catalytic activity, substrate activation and protection against non-specific cleavage of the fusion protein by restriction protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phenylalanine positively modulates the cAMP‐dependent phosphorylation and negatively modulates the vasopressin‐induced and okadaic‐acid‐induced phosphorylation of phenylalanine 4‐monooxygenase in intact rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Mutagenesis of the regulatory domain of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

PKU mutation (D143G) associated with an apparent high residual enzyme activity: expression of a kinetic variant form of phenylalanine hydroxylase in three different systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Automated docking with grid-based energy evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

VMD: visual molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Knowledge-based protein secondary structure assignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Size and charge isomer separation and estimation of molecular weights of proteins by disc gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Quantitative analysis of protein far UV circular dichroism spectra by neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

The structural basis of the recognition of phenylalanine and pterin cofactors by phenylalanine hydroxylase: implications for the catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

In vitro expression of 34 naturally occurring mutant variants of phenylalanine hydroxylase: correlation with metabolic phenotypes and susceptibility toward protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Electrostatic activation of rat phenylalanine hydroxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Further studies of the role of Ser-16 in the regulation of the activity of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Human liver type pyruvate kinase: complete amino acid sequence and the expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylation of serine-46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Pterin-Dependent Amino Acid Hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Substrate phosphorylation can inhibit proteolysis by trypsin-like enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

The hydroxypyridinium crosslinks of skeletal collagens: their measurement, properties and a proposed pathway of formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Domain structure and stability of human phenylalanine hydroxylase inferred from infrared spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

STARCH-GEL ELECTROPHORESIS--APPLICATION TO THE CLASSIFICATION OF PITUITARY PROTEINS AND POLYPEPTIDES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylation-induced structural change in phospholamban and its mutants, detected by intrinsic fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids. Effects on catalytic and stability properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Expression of wild type and mutant forms of human phenylalanine hydroxylase in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Conformational properties and stability of tyrosine hydroxylase studied by infrared spectroscopy. Effect of iron/catecholamine binding and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Protein kinase CK2 differentially phosphorylates maize chromosomal high mobility group B (HMGB) proteins modulating their stability and DNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

Phosphorylation stabilizes the N-termini of alpha-helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112197200

21 January 2018

Identifiers

DOI

10.1074/JBC.M112197200

1 reference

29 November 2017

1 reference