(Q44135807)

English

Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative

scientific article published in September 2002

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scholarly article

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Europe PubMed Central

30 November 2017

Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative (English)

1 reference

Europe PubMed Central

30 November 2017

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10

object named as

Bradley T Hyman

1 reference

Europe PubMed Central

30 November 2017

6

object named as

Matthew P Frosch

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Europe PubMed Central

30 November 2017

author name string

William E Klunk

1

1 reference

Europe PubMed Central

30 November 2017

Brian J Bacskai

2

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Europe PubMed Central

30 November 2017

Chester A Mathis

3

1 reference

Europe PubMed Central

30 November 2017

Stephen T Kajdasz

4

1 reference

Europe PubMed Central

30 November 2017

Megan E McLellan

5

1 reference

Europe PubMed Central

30 November 2017

Manik L Debnath

7

1 reference

Europe PubMed Central

30 November 2017

Daniel P Holt

8

1 reference

Europe PubMed Central

30 November 2017

Yanming Wang

9

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Europe PubMed Central

30 November 2017

language of work or name

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publication date

1 September 2002

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Europe PubMed Central

30 November 2017

Journal of Neuropathology & Experimental Neurology

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Europe PubMed Central

30 November 2017

61

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30 November 2017

9

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30 November 2017

797-805

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Europe PubMed Central

30 November 2017

Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease

1 reference

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Biological markers of Alzheimer's disease

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beta-peptide immunization: a possible new treatment for Alzheimer disease

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Regulation of APP cleavage by alpha-, beta- and gamma-secretases

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Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

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Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain.

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99mTc-MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease

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Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.

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Two-photon laser scanning fluorescence microscopy

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Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathy

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Analysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopy

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Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

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Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

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21 January 2018

X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology.

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Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay.

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Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.

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Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss

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Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain.

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Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

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Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

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Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography.

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[11C](+)McN5652 as a radiotracer for imaging serotonin uptake sites with PET.

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[11C]WAY 100635: a radioligand for imaging 5-HT1A receptors with positron emission tomography

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Relationship between immobilised artificial membrane chromatographic retention and the brain penetration of structurally diverse drugs

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Fundamentals of positron emission tomography and applications in preclinical drug development

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Use of positron emission tomography in animal research

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21 January 2018

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

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21 January 2018

In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease

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21 January 2018

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain

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IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain

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21 January 2018

Identifiers

10.1093/JNEN/61.9.797

1 reference

Europe PubMed Central

30 November 2017

1 reference

Europe PubMed Central

30 November 2017

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